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PDB: 10 results
4WAT
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BU of 4wat by Molmil
Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMIDAZOLE, PfRh5
Authors:Chen, L.
Deposit date:2014-09-01
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes.
Elife, 3, 2014
7PHU
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BU of 7phu by Molmil
PfRH5 bound to monoclonal antibody R5.015 and R5.016 Fab fragments
Descriptor: Monoclonal antibody R5.015 heavy chain, Monoclonal antibody R5.015 light chain, Monoclonal antibody R5.016 heavy chain, ...
Authors:Ragotte, R.J, Higgins, M.K.
Deposit date:2021-08-18
Release date:2022-02-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Heterotypic interactions drive antibody synergy against a malaria vaccine candidate.
Nat Commun, 13, 2022
5MI0
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BU of 5mi0 by Molmil
A thermally stabilised version of Plasmodium falciparum RH5
Descriptor: MONOCLONAL ANTIBODY 9AD4, Reticulocyte binding-like protein 5,Reticulocyte binding protein 5
Authors:Campeotto, I, Goldenzweig, A, Davey, J, Barfod, L, Marshall, J.M, Silk, S.E, Wright, K.E, Draper, S.J, Higgins, M.K, Fleishman, S.J.
Deposit date:2016-11-27
Release date:2016-12-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6RCU
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BU of 6rcu by Molmil
PfRH5 bound to monoclonal antibodies R5.004 and R5.016
Descriptor: R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ...
Authors:Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:2019-04-11
Release date:2019-06-26
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (4.005 Å)
Cite:Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCV
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BU of 6rcv by Molmil
PfRH5 bound to monoclonal antibodies R5.011 and R5.016
Descriptor: R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ...
Authors:Alanine, D.W.G, Draper, S.J, Higgins, M.K.
Deposit date:2019-04-11
Release date:2019-06-26
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (3.582 Å)
Cite:Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
4U0R
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BU of 4u0r by Molmil
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4
Descriptor: Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, Reticulocyte binding protein 5
Authors:Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K.
Deposit date:2014-07-14
Release date:2014-08-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014
4U1G
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BU of 4u1g by Molmil
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody QA1
Descriptor: QA1 monoclonal antibody heavy chain, QA1 monoclonal antibody light chain, Reticulocyte binding protein 5
Authors:Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K.
Deposit date:2014-07-15
Release date:2014-08-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014
8CDD
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BU of 8cdd by Molmil
PfRH5-PfCyRPA-PfRIPR complex from Plasmodium falciparum bound to antibody Cy.003
Descriptor: Cy.003 heavy chain, Cy.003 light chain, Cysteine-rich protective antigen, ...
Authors:Farrell, B, Higgins, M.K.
Deposit date:2023-01-30
Release date:2023-10-25
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The PfRCR complex bridges malaria parasite and erythrocyte during invasion.
Nature, 625, 2024
6MPV
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BU of 6mpv by Molmil
Cryo-electron microscopy structure of Plasmodium falciparum Rh5/CyRPA/Ripr invasion complex
Descriptor: Cysteine-rich protective antigen, PfRipr, Reticulocyte binding protein 5
Authors:Wilson, W, Zhiheng, Y, Cowman, A.F.
Deposit date:2018-10-08
Release date:2018-12-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.17 Å)
Cite:Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex.
Nature, 565, 2019
4U0Q
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BU of 4u0q by Molmil
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to basigin
Descriptor: Basigin, Reticulocyte binding protein 5
Authors:Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K.
Deposit date:2014-07-14
Release date:2014-08-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014

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