Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 51 results
5I7M
DownloadVisualize
BU of 5i7m by Molmil
Crystal structure of Y345F mutant of human primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
Authors:Salay, L.E, Thompson, M.K, Chazin, W.J.
Deposit date:2016-02-17
Release date:2017-03-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
3LGB
DownloadVisualize
BU of 3lgb by Molmil
Crystal Structure of the Fe-S Domain of the yeast DNA primase
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA primase large subunit, GLYCEROL, ...
Authors:Sauguet, L, Pellegrini, L.
Deposit date:2010-01-20
Release date:2010-04-21
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase
PLOS ONE, 5, 2010
3L9Q
DownloadVisualize
BU of 3l9q by Molmil
Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
Authors:Vaithiyalingam, S, Eichman, B.F, Chazin, W.J.
Deposit date:2010-01-05
Release date:2010-07-14
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3Q36
DownloadVisualize
BU of 3q36 by Molmil
Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit
Descriptor: DNA primase large subunit, FE (III) ION, IRON/SULFUR CLUSTER
Authors:Agarkar, V.B, Babayeva, N.D, Tahirov, T.H.
Deposit date:2010-12-21
Release date:2011-04-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase - polymerase alpha switch.
Cell Cycle, 10, 2011
2DLA
DownloadVisualize
BU of 2dla by Molmil
Primase large subunit amino terminal domain from Pyrococcus horikoshii
Descriptor: 397aa long hypothetical protein
Authors:Ito, N.
Deposit date:2006-04-17
Release date:2007-02-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular basis for the subunit assembly of the primase from an archaeon Pyrococcus horikoshii
Febs J., 274, 2007
5DQO
DownloadVisualize
BU of 5dqo by Molmil
Crystal structure of Y347F mutant of human primase p58 iron-sulfur cluster domain
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Thompson, M.K, Chazin, W.J.
Deposit date:2015-09-15
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
5F0S
DownloadVisualize
BU of 5f0s by Molmil
Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion
Descriptor: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ...
Authors:Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
Deposit date:2015-11-28
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
5F0Q
DownloadVisualize
BU of 5f0q by Molmil
Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer
Descriptor: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ...
Authors:Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
Deposit date:2015-11-28
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
7TL3
DownloadVisualize
BU of 7tl3 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF431
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.066 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL2
DownloadVisualize
BU of 7tl2 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF412
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ...
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL4
DownloadVisualize
BU of 7tl4 by Molmil
Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 6YF
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Blee, A.M, Salay, L.E, Chazin, W.J.
Deposit date:2022-01-18
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
6DHW
DownloadVisualize
BU of 6dhw by Molmil
Crystal structure of primase iron-sulfur domain (266-457)
Descriptor: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
Authors:Holt, M.E, Salay, L.E, Chazin, W.J.
Deposit date:2018-05-21
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.013 Å)
Cite:Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs.
PLoS ONE, 13, 2018
6DU0
DownloadVisualize
BU of 6du0 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395L mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ...
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DI6
DownloadVisualize
BU of 6di6 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-05-22
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DTV
DownloadVisualize
BU of 6dtv by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395F mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DI2
DownloadVisualize
BU of 6di2 by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y397L mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-05-22
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DTZ
DownloadVisualize
BU of 6dtz by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, ...
Authors:Salay, L.E, Chazin, W.J.
Deposit date:2018-06-18
Release date:2018-12-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4RR2
DownloadVisualize
BU of 4rr2 by Molmil
Crystal structure of human primase
Descriptor: DNA primase large subunit, DNA primase small subunit, IRON/SULFUR CLUSTER, ...
Authors:Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H.
Deposit date:2014-11-05
Release date:2015-01-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the human primase.
J.Biol.Chem., 290, 2015
7OPL
DownloadVisualize
BU of 7opl by Molmil
CryoEM structure of DNA Polymerase alpha - primase bound to SARS CoV nsp1
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2021-06-01
Release date:2021-11-10
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Structural basis for the interaction of SARS-CoV-2 virulence factor nsp1 with DNA polymerase alpha-primase.
Protein Sci., 31, 2022
8QJ7
DownloadVisualize
BU of 8qj7 by Molmil
Cryo-EM structure of human DNA polymerase alpha-primase in pre-initiation stage 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
Authors:Yin, Z, Pellegrini, L.
Deposit date:2023-09-12
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:CryoEM insights into RNA primer synthesis by the human primosome.
Febs J., 2024
5OFN
DownloadVisualize
BU of 5ofn by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
Descriptor: DNA primase large subunit PriL,PriL-X fusion protein, DNA primase small subunit PriS, ZINC ION
Authors:Pellegrini, L, Holzer, S.
Deposit date:2017-07-11
Release date:2017-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
5OF3
DownloadVisualize
BU of 5of3 by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA primase large subunit PriL, DNA primase small subunit PriS, ...
Authors:Pellegrini, L, Holzer, S.
Deposit date:2017-07-10
Release date:2017-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
1ZT2
DownloadVisualize
BU of 1zt2 by Molmil
Heterodimeric structure of the core primase.
Descriptor: DNA primase large subunit, DNA primase small subunit, SULFATE ION, ...
Authors:Lao-Sirieix, S.H, Nookala, R.K, Roversi, P, Bell, S.D, Pellegrini, L.
Deposit date:2005-05-26
Release date:2005-11-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structure of the heterodimeric core primase.
Nat.Struct.Mol.Biol., 12, 2005
5EXR
DownloadVisualize
BU of 5exr by Molmil
Crystal structure of human primosome
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
Authors:Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D.
Deposit date:2015-11-24
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
7U5C
DownloadVisualize
BU of 7u5c by Molmil
Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state
Descriptor: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ...
Authors:Cai, S.W, Zinder, J.C, Svetlov, V, Bush, M.W, Nudler, E, Walz, T, de Lange, T.
Deposit date:2022-03-02
Release date:2022-05-18
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-EM structure of the human CST-Pol alpha /primase complex in a recruitment state.
Nat.Struct.Mol.Biol., 29, 2022

 

123>

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon