3JCO
| Structure of yeast 26S proteasome in M1 state derived from Titan dataset | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F. | Deposit date: | 2016-01-06 | Release date: | 2016-06-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure of an endogenous yeast 26S proteasome reveals two major conformational states. Proc.Natl.Acad.Sci.USA, 113, 2016
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7P6U
| Lon protease from Thermus Thermophilus | Descriptor: | (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK), Lon protease, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Coscia, F, Lowe, J. | Deposit date: | 2021-07-18 | Release date: | 2021-10-27 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the full-length Lon protease from Thermus thermophilus. Febs Lett., 595, 2021
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3J99
| Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIb) | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | Deposit date: | 2014-12-05 | Release date: | 2015-01-28 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
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3J3T
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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3J96
| Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State I) | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | Deposit date: | 2014-12-05 | Release date: | 2015-01-28 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
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3J3R
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine J.Biol.Chem., 288, 2013
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7OXO
| human LonP1, R-state, incubated in AMPPCP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | Authors: | Abrahams, J.P, Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T. | Deposit date: | 2021-06-22 | Release date: | 2021-12-22 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
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3J3U
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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3J95
| Structure of ADP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Vesicle-fusing ATPase | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | Deposit date: | 2014-12-05 | Release date: | 2015-01-28 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
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3JCP
| Structure of yeast 26S proteasome in M2 state derived from Titan dataset | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Luan, B, Huang, X.L, Wu, J.P, Shi, Y.G, Wang, F. | Deposit date: | 2016-01-06 | Release date: | 2016-06-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure of an endogenous yeast 26S proteasome reveals two major conformational states. Proc.Natl.Acad.Sci.USA, 113, 2016
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3J94
| Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | Deposit date: | 2014-12-05 | Release date: | 2015-01-28 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
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3J3S
| Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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3J98
| Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa) | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | Deposit date: | 2014-12-05 | Release date: | 2015-01-28 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
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3J97
| Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II) | Descriptor: | Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... | Authors: | Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. | Deposit date: | 2014-12-05 | Release date: | 2015-01-28 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
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3KDS
| apo-FtsH crystal structure | Descriptor: | Cell division protein FtsH, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-naphthalen-2-yl-L-alanyl-L-alaninamide, ZINC ION | Authors: | Bieniossek, C, Niederhauser, B, Baumann, U. | Deposit date: | 2009-10-23 | Release date: | 2009-12-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | The crystal structure of apo-FtsH reveals domain movements necessary for substrate unfolding and translocation Proc.Natl.Acad.Sci.USA, 106, 2009
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7PXA
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7PXB
| Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state B) | Descriptor: | AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7PXC
| Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state A) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7PX9
| Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state A) | Descriptor: | AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7PXD
| Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state B) | Descriptor: | AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Jomaa, A, Kavalchuk, M, Weber-Ban, E. | Deposit date: | 2021-10-08 | Release date: | 2022-01-19 | Last modified: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex. Nat Commun, 13, 2022
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7PUX
| Structure of p97 N-D1(L198W) in complex with Fragment TROLL2 | Descriptor: | (1S)-2-amino-1-(4-bromophenyl)ethan-1-ol, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bothe, S, Schindelin, H. | Deposit date: | 2021-10-01 | Release date: | 2022-12-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97 Commun Chem, 5, 2022
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7QO6
| 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | Deposit date: | 2021-12-23 | Release date: | 2022-03-16 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
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7QO5
| 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | Deposit date: | 2021-12-23 | Release date: | 2022-03-16 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
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7QO4
| 26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS) | Descriptor: | 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | Deposit date: | 2021-12-23 | Release date: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
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3M6A
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