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PDB: 21 results

6TRN
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Crystal structure of HLA A2*01-AVYDGREHTV
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239) variant, ...
Authors:Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S.
Deposit date:2019-12-19
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
J.Biol.Chem., 295, 2020
8FU4
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BU of 8fu4 by Molmil
HCMV US11 peptide binding to HLA-A*02:01
Descriptor: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
Authors:Watson, G.M, Berry, R, Littler, D.R, Rossjohn, J.
Deposit date:2023-01-16
Release date:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids.
Proc.Natl.Acad.Sci.USA, 121, 2024
7UM2
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BU of 7um2 by Molmil
SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01
Descriptor: Beta-2-microglobulin, CADMIUM ION, HLA class I antigen, ...
Authors:Szeto, C, Gras, S.
Deposit date:2022-04-06
Release date:2023-04-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:SARS-CoV-2 Spike-derived peptide S417-425 K417T mutant (TIADYNYKL) presented by HLA-A*02:01
To Be Published
7U1R
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BU of 7u1r by Molmil
SARS-CoV-2 Spike-derived peptide S1185-1193 K1191N mutant (RLNEVANNL) presented by HLA-A*02:01
Descriptor: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ...
Authors:Szeto, C, Gras, S.
Deposit date:2022-02-22
Release date:2023-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SARS-CoV-2 Spike-derived peptide S1185-1193 K1191N mutant (RLNEVANNL) presented by HLA-A*02:01
To Be Published
8RBV
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BU of 8rbv by Molmil
SARS-CoV-2 Spike-derived peptide S976-984 S982A mutant (VLNDILARL) presented by HLA-A*02:01
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
Authors:Ahn, Y.M, Maddumage, J.C, Szeto, C, Gras, S.
Deposit date:2023-12-05
Release date:2024-05-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Curr Res Struct Biol, 7, 2024
7RTD
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BU of 7rtd by Molmil
SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01
Descriptor: Beta-2-microglobulin, HLA class I antigen, Spike protein S1
Authors:Szeto, C, Nguyen, A.T, Gras, S.
Deposit date:2021-08-13
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR.
Cells, 10, 2021
8TBW
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BU of 8tbw by Molmil
Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) peptide KLSHQPVLL
Descriptor: Beta-2-microglobulin, HLA-A*02:01 alpha chain, NITRATE ION, ...
Authors:Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M.
Deposit date:2023-06-29
Release date:2024-01-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.081 Å)
Cite:Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
7UR1
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BU of 7ur1 by Molmil
SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) presented by HLA-A*02:01
Descriptor: Beta-2-microglobulin, HLA class I antigen, SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL)
Authors:Szeto, C, Ahn, Y.M, Gras, S.
Deposit date:2022-04-21
Release date:2023-04-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:SARS-CoV-2 Spike-derived peptide S1215-1224 (YIWLGFIAGL) presented by HLA-A*02:01
To Be Published
6UJO
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HHAT L75F Neoantigen Peptide KQWLVWLFL Presented by HLA-A206
Descriptor: Beta-2-microglobulin, MHC class I antigen, Protein-cysteine N-palmitoyltransferase HHAT
Authors:Devlin, J.R, Baker, B.M, Vander Kooi, C.
Deposit date:2019-10-03
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
6UJQ
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BU of 6ujq by Molmil
HHAT Wild Type Peptide KQWLVWLLL Presented by HLA-A206
Descriptor: Beta-2-microglobulin, MHC class I antigen, Protein-cysteine N-palmitoyltransferase HHAT
Authors:Devlin, J.R, Baker, B.M, Singh, N.K.
Deposit date:2019-10-03
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
3TO2
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BU of 3to2 by Molmil
Structure of HLA-A*0201 complexed with peptide Md3-C9 derived from a clustering region of restricted cytotoxic T lymphocyte epitope from SARS-CoV M protein
Descriptor: Beta-2-microglobulin, MHC class I antigen, Md3-C9 peptide derived from Membrane glycoprotein
Authors:Liu, J, Qi, J, Gao, F, Yan, J, Gao, G.F.
Deposit date:2011-09-03
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional and Structural Definition of a Clustering Region of HLA-A2-restricted Cytotoxic T Lymphocyte Epitopes
Sci.Technology Rev., 29, 2011
7RTR
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BU of 7rtr by Molmil
YLQ-SG3 TCR in complex with SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01
Descriptor: Beta-2-microglobulin, HLA class I antigen, SODIUM ION, ...
Authors:Szeto, C, Gras, S.
Deposit date:2021-08-14
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR.
Cells, 10, 2021
8TBV
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BU of 8tbv by Molmil
Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) neoantigen KLSHQLVLL
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M.
Deposit date:2023-06-29
Release date:2024-01-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
6UK4
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BU of 6uk4 by Molmil
Complex of T cell Receptor with HHAT Neoantigen Peptide KQWLVWLFL Presented by HLA-A206
Descriptor: 302 TIL T cell receptor alpha chain, 302 TIL T cell receptor beta chain, Beta-2-microglobulin, ...
Authors:Devlin, J.R, Baker, B.M.
Deposit date:2019-10-04
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
8U9G
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BU of 8u9g by Molmil
Human Class I MHC HLA-A2 bound to sorting nexin 24 (127-135) neoantigen KLSHQLVLL
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M.
Deposit date:2023-09-19
Release date:2024-01-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
8EB2
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BU of 8eb2 by Molmil
Structure of HLA-A*02:01 in complex with NY-ESO-1 peptide and PA2.1 Fab
Descriptor: Beta-2-microglobulin, HLA-A*02:01 alpha chain, NY-ESO-1 peptide, ...
Authors:Jette, C.A, West, A.P.
Deposit date:2022-08-30
Release date:2022-11-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
Mol Ther Oncolytics, 27, 2022
6TRO
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BU of 6tro by Molmil
Crystal structure of the T-cell receptor GVY01 bound to HLA A2*01-GVYDGREHTV
Descriptor: Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239), MHC class I antigen, ...
Authors:Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S.
Deposit date:2019-12-19
Release date:2020-06-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
J.Biol.Chem., 295, 2020
6P64
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BU of 6p64 by Molmil
Alpha-beta TCR Binding to Neoantigen KQWLVWLFL Presented by HLA-A206
Descriptor: 302TIL TCR alpha chain, 302TIL TCR beta chain, Beta-2-microglobulin, ...
Authors:Devlin, J.R, Baker, B.M.
Deposit date:2019-05-31
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:A T cell receptor peptide/MHC complex at 3.05 Angstrom resolution
To be Published
8ESB
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BU of 8esb by Molmil
CryoEM structure of HLA-A2 bound to MAGEA8 (232-241) peptide
Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A8 peptide chimera
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-10-13
Release date:2023-05-03
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
6UK2
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BU of 6uk2 by Molmil
Complex of T cell Receptor with HHAT Wild Type Peptide KQWLVWLLL Presented by HLA-A206
Descriptor: 302 TIL T cell receptor alpha chain, 302 TIL T cell receptor beta chain, Beta-2-microglobulin, ...
Authors:Devlin, J.R, Baker, B.M.
Deposit date:2019-10-04
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.138808 Å)
Cite:Structural dissimilarity from self drives neoepitope escape from immune tolerance.
Nat.Chem.Biol., 16, 2020
8ESA
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BU of 8esa by Molmil
CryoEM structure of HLA-A2 bound to MAGEA4 (230-239) peptide
Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A4 peptide chimera
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-10-13
Release date:2023-05-03
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023

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PDB entries from 2024-09-04

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