1XJV
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3KJP
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![BU of 3kjp by Molmil](/molmil-images/mine/3kjp) | Crystal Structure of hPOT1V2-GGTTAGGGTTAG | Descriptor: | 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3', Protection of telomeres protein 1 | Authors: | Nandakumar, J, Cech, T.R, Podell, E.R. | Deposit date: | 2009-11-03 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KJO
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![BU of 3kjo by Molmil](/molmil-images/mine/3kjo) | Crystal Structure of hPOT1V2-dTrUd(AGGGTTAG) | Descriptor: | DNA/RNA (5'-D(*T)-R(P*U)-D(P*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1 | Authors: | Nandakumar, J, Cech, T.R, Podell, E.R. | Deposit date: | 2009-11-03 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA. Proc.Natl.Acad.Sci.USA, 107, 2010
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5H65
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![BU of 5h65 by Molmil](/molmil-images/mine/5h65) | Crystal structure of human POT1 and TPP1 | Descriptor: | Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION | Authors: | Chen, C, Wu, J, Lei, M. | Deposit date: | 2016-11-10 | Release date: | 2017-05-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer. Nat Commun, 8, 2017
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5UN7
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![BU of 5un7 by Molmil](/molmil-images/mine/5un7) | Structure of the human POT1-TPP1 telomeric complex | Descriptor: | Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ... | Authors: | Rice, C, Doukov, T, Skordalakes, E. | Deposit date: | 2017-01-30 | Release date: | 2017-04-12 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional analysis of the human POT1-TPP1 telomeric complex. Nat Commun, 8, 2017
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8SH0
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7S1O
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![BU of 7s1o by Molmil](/molmil-images/mine/7s1o) | Structure of human POT1C | Descriptor: | Protection of telomeres protein 1, ZINC ION | Authors: | Aramburu, T, Skordalakes, E. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance. Comput Struct Biotechnol J, 20, 2022
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7S1U
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![BU of 7s1u by Molmil](/molmil-images/mine/7s1u) | Structure of human POT1C | Descriptor: | Protection of telomeres protein 1, ZINC ION | Authors: | Aramburu, T, Skordalakes, E. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance. Comput Struct Biotechnol J, 20, 2022
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8SH1
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7S1T
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![BU of 7s1t by Molmil](/molmil-images/mine/7s1t) | Structure of the human POT1-TPP1 complex | Descriptor: | Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION | Authors: | Aramburu, T, Skordalakes, E. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance. Comput Struct Biotechnol J, 20, 2022
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8SOJ
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7QXS
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![BU of 7qxs by Molmil](/molmil-images/mine/7qxs) | Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains) | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | Deposit date: | 2022-01-27 | Release date: | 2022-03-02 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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7QXB
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![BU of 7qxb by Molmil](/molmil-images/mine/7qxb) | Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map) | Descriptor: | Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... | Authors: | Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. | Deposit date: | 2022-01-26 | Release date: | 2022-03-02 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
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8SOK
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![BU of 8sok by Molmil](/molmil-images/mine/8sok) | |