6LAN
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![BU of 6lan by Molmil](/molmil-images/mine/6lan) | Structure of CCDC50 and LC3B complex | Descriptor: | Coiled-coil domain-containing protein 50,Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Liu, L, Li, J, Hou, P. | Deposit date: | 2019-11-12 | Release date: | 2020-09-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection. Cell Res., 31, 2021
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5MS5
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![BU of 5ms5 by Molmil](/molmil-images/mine/5ms5) | Low-salt structure of RavZ LIR2-fused human LC3B | Descriptor: | GLYCEROL, RavZ,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Pantoom, S, Vetter, I.R, Wu, Y.W. | Deposit date: | 2016-12-31 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins. Elife, 6, 2017
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5D94
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![BU of 5d94 by Molmil](/molmil-images/mine/5d94) | Crystal structure of LC3-LIR peptide complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FYVE and coiled-coil domain-containing protein 1 | Authors: | Takagi, K, Mizushima, T, Johansen, T. | Deposit date: | 2015-08-18 | Release date: | 2015-10-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy J.Biol.Chem., 290, 2015
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2ZJD
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![BU of 2zjd by Molmil](/molmil-images/mine/2zjd) | Crystal Structure of LC3-p62 complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B precursor, undecameric peptide from Sequestosome-1 | Authors: | Ichimura, Y, Kumanomidou, T, Sou, Y, Mizushima, T, Ezaki, J, Ueno, T, Kominami, E, Yamane, T, Tanaka, K, Komatsu, M. | Deposit date: | 2008-03-05 | Release date: | 2008-06-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structural Basis for Sorting Mechanism of p62 in Selective Autophagy J.Biol.Chem., 283, 2008
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7ELG
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![BU of 7elg by Molmil](/molmil-images/mine/7elg) | LC3B modificated with a covalent probe | Descriptor: | 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Fan, S, Wan, W. | Deposit date: | 2021-04-10 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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3VTU
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![BU of 3vtu by Molmil](/molmil-images/mine/3vtu) | Crystal structure of human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
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3VTV
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![BU of 3vtv by Molmil](/molmil-images/mine/3vtv) | Crystal structure of Optineurin LIR-fused human LC3B_2-119 | Descriptor: | Optineurin, microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
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5XAC
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![BU of 5xac by Molmil](/molmil-images/mine/5xac) | CLIR - LC3B | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-03-12 | Release date: | 2017-07-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | A novel conformation of the LC3-interacting region motif revealed by the structure of a complex between LC3B and RavZ Biochem. Biophys. Res. Commun., 490, 2017
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5XAD
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![BU of 5xad by Molmil](/molmil-images/mine/5xad) | NLIR - LC3B fusion protein | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Uncharacterised protein | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-03-12 | Release date: | 2017-07-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | A novel conformation of the LC3-interacting region motif revealed by the structure of a complex between LC3B and RavZ Biochem. Biophys. Res. Commun., 490, 2017
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6J04
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![BU of 6j04 by Molmil](/molmil-images/mine/6j04) | |
5MS6
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![BU of 5ms6 by Molmil](/molmil-images/mine/5ms6) | |
5XAE
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![BU of 5xae by Molmil](/molmil-images/mine/5xae) | mutNLIR_LC3B | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-03-12 | Release date: | 2017-07-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.996 Å) | Cite: | A novel conformation of the LC3-interacting region motif revealed by the structure of a complex between LC3B and RavZ Biochem. Biophys. Res. Commun., 490, 2017
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5DCN
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![BU of 5dcn by Molmil](/molmil-images/mine/5dcn) | Crystal structure of LC3 in complex with TECPR2 LIR | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Stadel, D, Huber, J, Dotsch, V, Rogov, V.V, Behrends, C, Akutsu, M. | Deposit date: | 2015-08-24 | Release date: | 2016-03-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export. Mol.Cell, 60, 2015
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5V4K
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![BU of 5v4k by Molmil](/molmil-images/mine/5v4k) | Crystal structure of NEDD4 LIR-fused human LC3B_2-119 | Descriptor: | GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Qiu, Y, Zheng, Y, Schulman, B. | Deposit date: | 2017-03-09 | Release date: | 2017-05-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4. Protein Sci., 26, 2017
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5GMV
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![BU of 5gmv by Molmil](/molmil-images/mine/5gmv) | LC3B-FUNDC1 complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FUN14 domain-containing protein 1 | Authors: | Lv, M, Wang, C, Li, F. | Deposit date: | 2016-07-17 | Release date: | 2017-03-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy Protein Cell, 8, 2017
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4WAA
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![BU of 4waa by Molmil](/molmil-images/mine/4waa) | Crystal structure of Nix LIR-fused human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S. | Deposit date: | 2014-08-29 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins. Sci Rep, 7, 2017
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5MS2
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![BU of 5ms2 by Molmil](/molmil-images/mine/5ms2) | |
3VTW
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![BU of 3vtw by Molmil](/molmil-images/mine/3vtw) | Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 | Descriptor: | Optineurin, microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
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3WAO
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![BU of 3wao by Molmil](/molmil-images/mine/3wao) | Crystal structure of Atg13 LIR-fused human LC3B_2-119 | Descriptor: | Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | Deposit date: | 2013-05-06 | Release date: | 2013-12-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism. Structure, 22, 2014
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3X0W
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![BU of 3x0w by Molmil](/molmil-images/mine/3x0w) | Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, McEwan, D.G, Popovic, D, Gubas, A, Terawaki, S, Stadel, D, Coxon, F, Stegmann, D.M, Bhogaraju, S, Maddi, K, Kirchhoff, A, Gatti, E, Helfrich, M.H, Behrends, C, Pierre, P, Dikic, I, Wakatsuki, S. | Deposit date: | 2014-10-22 | Release date: | 2015-01-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. Mol.Cell, 57, 2015
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5W9A
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![BU of 5w9a by Molmil](/molmil-images/mine/5w9a) | The structure of the Trim5alpha Bbox- coiled coil in complex LC3B | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Tripartite motif-containing protein 5, ZINC ION | Authors: | Keown, J.R, Goldstone, D.C. | Deposit date: | 2017-06-22 | Release date: | 2018-10-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5 alpha and mammalian autophagy-related ATG8 proteins. J. Biol. Chem., 293, 2018
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2LUE
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![BU of 2lue by Molmil](/molmil-images/mine/2lue) | LC3B OPTN-LIR Ptot complex structure | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Optineurin | Authors: | Rogov, V.V, Rozenknop, A, Loehr, F, Guentert, P, Doetsch, V. | Deposit date: | 2012-06-13 | Release date: | 2013-07-17 | Last modified: | 2022-08-24 | Method: | SOLUTION NMR | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella. Biochem.J., 454, 2013
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1V49
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![BU of 1v49 by Molmil](/molmil-images/mine/1v49) | Solution structure of microtubule-associated protein light chain-3 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Kouno, T, Mizuguchi, M, Tanida, I, Ueno, T, Kominami, E, Kawano, K. | Deposit date: | 2003-11-11 | Release date: | 2004-12-28 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. J.Biol.Chem., 280, 2005
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2N9X
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![BU of 2n9x by Molmil](/molmil-images/mine/2n9x) | LC3 FUNDC1 complex structure | Descriptor: | FUN14 domain-containing protein 1, Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Xia, B, Kuang, Y. | Deposit date: | 2015-12-14 | Release date: | 2016-12-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy. Autophagy, 12, 2016
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