5W9A
The structure of the Trim5alpha Bbox- coiled coil in complex LC3B
Summary for 5W9A
| Entry DOI | 10.2210/pdb5w9a/pdb |
| Descriptor | Tripartite motif-containing protein 5, Microtubule-associated proteins 1A/1B light chain 3B, ZINC ION (3 entities in total) |
| Functional Keywords | autophagy trim5alpha lc3b antiviral protein, antiviral protein |
| Biological source | Macaca mulatta (Rhesus macaque) More |
| Total number of polymer chains | 4 |
| Total formula weight | 73395.26 |
| Authors | Keown, J.R.,Goldstone, D.C. (deposition date: 2017-06-22, release date: 2018-10-10, Last modification date: 2023-10-04) |
| Primary citation | Keown, J.R.,Black, M.M.,Ferron, A.,Yap, M.,Barnett, M.J.,Pearce, F.G.,Stoye, J.P.,Goldstone, D.C. A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5 alpha and mammalian autophagy-related ATG8 proteins. J. Biol. Chem., 293:18378-18386, 2018 Cited by PubMed: 30282803DOI: 10.1074/jbc.RA118.004202 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.74 Å) |
Structure validation
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