5W9A

The structure of the Trim5alpha Bbox- coiled coil in complex LC3B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
B	0008270	molecular_function	zinc ion binding
C	0000045	biological_process	autophagosome assembly
C	0000421	cellular_component	autophagosome membrane
C	0000422	biological_process	autophagy of mitochondrion
C	0000423	biological_process	mitophagy
C	0005515	molecular_function	protein binding
C	0005543	molecular_function	phospholipid binding
C	0005739	cellular_component	mitochondrion
C	0005776	cellular_component	autophagosome
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0005930	cellular_component	axoneme
C	0006914	biological_process	autophagy
C	0006995	biological_process	cellular response to nitrogen starvation
C	0008017	molecular_function	microtubule binding
C	0008429	molecular_function	phosphatidylethanolamine binding
C	0009267	biological_process	cellular response to starvation
C	0012505	cellular_component	endomembrane system
C	0016020	cellular_component	membrane
C	0016236	biological_process	macroautophagy
C	0031090	cellular_component	organelle membrane
C	0031410	cellular_component	cytoplasmic vesicle
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0031966	cellular_component	mitochondrial membrane
C	0097001	molecular_function	ceramide binding
C	0097352	biological_process	autophagosome maturation
D	0000045	biological_process	autophagosome assembly
D	0000421	cellular_component	autophagosome membrane
D	0000422	biological_process	autophagy of mitochondrion
D	0000423	biological_process	mitophagy
D	0005515	molecular_function	protein binding
D	0005543	molecular_function	phospholipid binding
D	0005739	cellular_component	mitochondrion
D	0005776	cellular_component	autophagosome
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0005930	cellular_component	axoneme
D	0006914	biological_process	autophagy
D	0006995	biological_process	cellular response to nitrogen starvation
D	0008017	molecular_function	microtubule binding
D	0008429	molecular_function	phosphatidylethanolamine binding
D	0009267	biological_process	cellular response to starvation
D	0012505	cellular_component	endomembrane system
D	0016020	cellular_component	membrane
D	0016236	biological_process	macroautophagy
D	0031090	cellular_component	organelle membrane
D	0031410	cellular_component	cytoplasmic vesicle
D	0031625	molecular_function	ubiquitin protein ligase binding
D	0031966	cellular_component	mitochondrial membrane
D	0097001	molecular_function	ceramide binding
D	0097352	biological_process	autophagosome maturation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 301

Chain	Residue
A	CYS97
A	HIS100
A	CYS116
A	CYS119

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 302

Chain	Residue
A	CYS108
A	ASP111
A	HIS125
A	HIS128

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 301

Chain	Residue
B	HIS100
B	CYS116
B	CYS119
B	CYS97

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN B 302

Chain	Residue
B	CYS108
B	ASP111
B	HIS125
B	HIS128

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Region: {"description":"Required for interaction with GABARAP and for autophagy","evidences":[{"source":"PubMed","id":"25127057","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	176
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00024","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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