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PDB: 10 results

4RCJ
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BU of 4rcj by Molmil
Crystal structure of YTHDF1 YTH domain in complex with 5mer m6A RNA
Descriptor: RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, YTH domain-containing family protein 1
Authors:Tempel, W, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-09-16
Release date:2014-11-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
4RCI
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BU of 4rci by Molmil
Crystal structure of YTHDF1 YTH domain
Descriptor: UNKNOWN ATOM OR ION, YTH domain-containing family protein 1
Authors:Xu, C, Tempel, W, Liu, K, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-09-16
Release date:2014-10-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
7YYE
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BU of 7yye by Molmil
Orthorombic crystal structure of YTHDF1 YTH domain (G459N mutant) form I
Descriptor: 1,2-ETHANEDIOL, MALONIC ACID, YTH domain-containing family protein 1
Authors:Dalle Vedove, A, Cazzanelli, G, Lolli, G.
Deposit date:2022-02-17
Release date:2023-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pliability in the m 6 A-Binding Region Extends Druggability of YTH Domains.
J.Chem.Inf.Model., 2024
7YYJ
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BU of 7yyj by Molmil
Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)
Descriptor: 1,2-ETHANEDIOL, THIOCYANATE ION, YTH domain-containing family protein 1
Authors:Dalle Vedove, A, Cazzanelli, G, Lolli, G.
Deposit date:2022-02-18
Release date:2023-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pliability in the m 6 A-Binding Region Extends Druggability of YTH Domains.
J.Chem.Inf.Model., 2024
8BS4
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BU of 8bs4 by Molmil
Crystal structure of YTHDF1 YTH domain dimer
Descriptor: ACETATE ION, GLYCEROL, YTH domain-containing family protein 1
Authors:Bedi, R.K, Caflisch, A.
Deposit date:2022-11-24
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of YTHDF1 YTH domain dimer
To Be Published
7QKN
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BU of 7qkn by Molmil
Crystal structure of YTHDF1 YTH domain in complex with the ebsulfur derivative compound 7
Descriptor: 1,2-ETHANEDIOL, THIOCYANATE ION, YTH domain-containing family protein 1, ...
Authors:Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G.
Deposit date:2021-12-18
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs.
Acs Pharmacol Transl Sci, 5, 2022
7YYF
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BU of 7yyf by Molmil
Orthorombic crystal structure of YTHDF1 YTH domain (G459N mutant) form II
Descriptor: YTH domain-containing family protein 1
Authors:Dalle Vedove, A, Cazzanelli, G, Lolli, G.
Deposit date:2022-02-17
Release date:2023-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Pliability in the m 6 A-Binding Region Extends Druggability of YTH Domains.
J.Chem.Inf.Model., 2024
7QL7
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BU of 7ql7 by Molmil
Crystal structure of YTHDF1 YTH domain in complex with the ebsulfur derivative compound 9
Descriptor: 1,2-ETHANEDIOL, THIOCYANATE ION, YTH domain-containing family protein 1, ...
Authors:Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G.
Deposit date:2021-12-19
Release date:2022-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs.
Acs Pharmacol Transl Sci, 5, 2022
7YZ8
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BU of 7yz8 by Molmil
Triclinic crystal structure of YTHDF1 YTH domain (544AVV546 mutant)
Descriptor: THIOCYANATE ION, YTH domain-containing family protein 1
Authors:Dalle Vedove, A, Cazzanelli, G, Lolli, G.
Deposit date:2022-02-19
Release date:2023-03-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pliability in the m 6 A-Binding Region Extends Druggability of YTH Domains.
J.Chem.Inf.Model., 2024
7PCU
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BU of 7pcu by Molmil
Crystal structure of YTHDF1 YTH domain in complex with ebselen
Descriptor: N-phenyl-2-selanylbenzamide, YTH domain-containing family protein 1
Authors:Dalle Vedove, A, Cazzanelli, G, Quattrone, A, Provenzani, A, Lolli, G.
Deposit date:2021-08-04
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6 -Methyladenosine-Modified RNAs.
Acs Pharmacol Transl Sci, 5, 2022

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PDB entries from 2024-07-17

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