7YYJ
Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)
Summary for 7YYJ
Entry DOI | 10.2210/pdb7yyj/pdb |
Related | 7YYE 7YYF |
Descriptor | YTH domain-containing family protein 1, 1,2-ETHANEDIOL, THIOCYANATE ION, ... (4 entities in total) |
Functional Keywords | mrna binding and stability, rna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 46660.77 |
Authors | Dalle Vedove, A.,Cazzanelli, G.,Lolli, G. (deposition date: 2022-02-18, release date: 2023-03-01, Last modification date: 2024-03-13) |
Primary citation | Cazzanelli, G.,Dalle Vedove, A.,Spagnolli, G.,Terruzzi, L.,Colasurdo, E.,Boldrini, A.,Patsilinakos, A.,Sturlese, M.,Grottesi, A.,Biasini, E.,Provenzani, A.,Quattrone, A.,Lolli, G. Pliability in the m 6 A-Binding Region Extends Druggability of YTH Domains. J.Chem.Inf.Model., 2024 Cited by PubMed: 38417111DOI: 10.1021/acs.jcim.4c00051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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