7YYJ
Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | YTH domain-containing family protein 1 | polymer | 200 | 23148.2 | 2 | UniProt (Q9BYJ9) Pfam (PF04146) | Homo sapiens (human) | DF1,Dermatomyositis associated with cancer putative autoantigen 1,DACA-1 |
| 2 | C, D, F, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | E, G (A, B) | THIOCYANATE ION | non-polymer | 58.1 | 2 | Chemie (SCN) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A, B: 361 - 559 (UniProt: Q9BYJ9)
| PDB | External Database | Details |
|---|---|---|
| Gly 360 | - | expression tag |
| Ala 544 | Glu 544 | engineered mutation |
| Val 545 | Glu 545 | engineered mutation |
| Val 546 | Glu 546 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46296.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 364.4 | |
| All* | Total formula weight | 46660.8 |
