7YZ8

Triclinic crystal structure of YTHDF1 YTH domain (544AVV546 mutant)

Summary for 7YZ8

Entry DOI	10.2210/pdb7yz8/pdb
Related	7YYE 7YYF 7YYJ
Descriptor	YTH domain-containing family protein 1, THIOCYANATE ION (3 entities in total)
Functional Keywords	mrna binding and stability, rna binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	12
Total formula weight	278474.98
Authors	Dalle Vedove, A.,Cazzanelli, G.,Lolli, G. (deposition date: 2022-02-19, release date: 2023-03-01, Last modification date: 2024-03-13)
Primary citation	Cazzanelli, G.,Dalle Vedove, A.,Spagnolli, G.,Terruzzi, L.,Colasurdo, E.,Boldrini, A.,Patsilinakos, A.,Sturlese, M.,Grottesi, A.,Biasini, E.,Provenzani, A.,Quattrone, A.,Lolli, G. Pliability in the m 6 A-Binding Region Extends Druggability of YTH Domains. J.Chem.Inf.Model., 2024 Cited by PubMed: 38417111 DOI: 10.1021/acs.jcim.4c00051 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation