1VHH
 
 | | A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG | | Descriptor: | SONIC HEDGEHOG, SULFATE ION, ZINC ION | | Authors: | Hall, T.M.T, Porter, J.A, Beachy, P.A, Leahy, D.J. | | Deposit date: | 1995-10-03 | | Release date: | 1996-01-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Nature, 378, 1995
|
|
3D1M
 | |
4C4M
 | | Crystal structure of the Sonic Hedgehog-chondroitin-4-sulphate complex | | Descriptor: | ACETATE ION, CALCIUM ION, SONIC HEDGEHOG PROTEIN, ... | | Authors: | Whalen, D.M, Malinauskas, T, Gilbert, R.J.C, Siebold, C. | | Deposit date: | 2013-09-05 | | Release date: | 2013-10-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structural Insights Into Proteoglycan-Shaped Hedgehog Signaling.
Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
3N1R
 | | Crystal Structure of ShhN | | Descriptor: | CALCIUM ION, Sonic hedgehog protein, ZINC ION | | Authors: | Kavran, J.M, Leahy, D.J. | | Deposit date: | 2010-05-16 | | Release date: | 2010-06-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Crystal Structure of ShhN
TO BE PUBLISHED
|
|
4C4N
 | | Crystal structure of the Sonic Hedgehog-heparin complex | | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, ... | | Authors: | Whalen, D.M, Malinauskas, T, Gilbert, R.J.C, Siebold, C. | | Deposit date: | 2013-09-05 | | Release date: | 2013-10-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structural Insights Into Proteoglycan-Shaped Hedgehog Signaling.
Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
7RPK
 | | Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog | | Descriptor: | (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | | Deposit date: | 2021-08-03 | | Release date: | 2021-10-27 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
|
|
2WG4
 | | Crystal structure of the complex between human hedgehog-interacting protein HIP and sonic hedgehog without calcium | | Descriptor: | HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, SONIC HEDGEHOG PROTEIN N-PRODUCT, ... | | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | Deposit date: | 2009-04-15 | | Release date: | 2009-06-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
|
|
2WFX
 | | Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium | | Descriptor: | CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ... | | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | Deposit date: | 2009-04-15 | | Release date: | 2009-06-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
|
|
