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PDB: 5 results

5AGI
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BU of 5agi by Molmil
Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP
Descriptor: GLYCEROL, POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE
Authors:Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A.
Deposit date:2015-02-02
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
5AGH
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BU of 5agh by Molmil
Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A
Descriptor: ACETATE ION, POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE
Authors:Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A.
Deposit date:2015-02-02
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
5AGJ
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BU of 5agj by Molmil
Crystal structure of the LeuRS editing domain of Candida albicans in complex with the adduct AN2690-AMP
Descriptor: POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE
Authors:Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A.
Deposit date:2015-02-02
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
2WFG
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BU of 2wfg by Molmil
Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct
Descriptor: CYTOSOLIC LEUCYL-TRNA SYNTHETASE, [(1S,3S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-4'-ETHYLAMINO-3'-FLUORO-SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,7'-8-OXA-7-BORANUIDABICYCLO[4.3.0]NONA-1,3,5-TRIENE]-8-YL]METHYL DIHYDROGEN PHOSPHATE
Authors:Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S.
Deposit date:2009-04-05
Release date:2009-05-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles.
J.Mol.Biol., 390, 2009
2WFE
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BU of 2wfe by Molmil
Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain
Descriptor: CYTOSOLIC LEUCYL-TRNA SYNTHETASE
Authors:Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S.
Deposit date:2009-04-04
Release date:2009-05-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles.
J.Mol.Biol., 390, 2009

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