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PDB: 6 results
6ES1
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BU of 6es1 by Molmil
Crystal structure of the binding domain from botulinum neurotoxin A2 bound to extracellular domain of human receptor SV2C
Descriptor: ACETATE ION, Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Gustafsson, R, Masuyer, G, Stenmark, P.
Deposit date:2017-10-19
Release date:2018-04-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.
Toxins (Basel), 10, 2018
5JLV
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BU of 5jlv by Molmil
Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
4JRA
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BU of 4jra by Molmil
CRYSTAL STRUCTURE OF THE BOTULINUM NEUROTOXIN A RECEPTOR-BINDING DOMAIN IN COMPLEX WITH THE LUMINAL DOMAIN Of SV2C
Descriptor: Botulinum neurotoxin type A, CHLORIDE ION, SODIUM ION, ...
Authors:Benoit, R.M, Frey, D, Wieser, M.M, Jaussi, R, Schertler, G.F.X, Capitani, G, Kammerer, R.A.
Deposit date:2013-03-21
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.
Nature, 505, 2014
5MOY
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BU of 5moy by Molmil
Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C
Descriptor: 1,2-ETHANEDIOL, Botulinum neurotoxin type A, NONAETHYLENE GLYCOL, ...
Authors:Benoit, R.M, Scharer, M.A.
Deposit date:2016-12-14
Release date:2017-03-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C.
Sci Rep, 7, 2017
7UIA
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BU of 7uia by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Liu, Z, Jin, R, Chen, P.
Deposit date:2022-03-28
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIB
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BU of 7uib by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ...
Authors:Liu, Z, Jin, R, Chen, P.
Deposit date:2022-03-29
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023

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