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PDB: 10 results

5VBN
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Crystal Structure of human DNA polymerase epsilon B-subunit in complex with C-terminal domain of catalytic subunit
Descriptor: DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit 2, SULFATE ION, ...
Authors:Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H.
Deposit date:2017-03-29
Release date:2017-08-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the human Pol B-subunit in complex with the C-terminal domain of the catalytic subunit.
J. Biol. Chem., 292, 2017
7PLO
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H. sapiens replisome-CUL2/LRR1 complex
Descriptor: Cell division control protein 45 homolog, Claspin, Cullin-2, ...
Authors:Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M.
Deposit date:2021-09-01
Release date:2021-11-10
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PFO
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Core human replisome
Descriptor: Cell division control protein 45 homolog, Claspin, DNA polymerase epsilon catalytic subunit A, ...
Authors:Jones, M.J, Yeeles, J.T.P.
Deposit date:2021-08-11
Release date:2021-11-10
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of a human replisome shows the organisation and interactions of a DNA replication machine.
Embo J., 40, 2021
9F6I
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BU of 9f6i by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state)
Descriptor: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA nascent strand, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6D
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Human DNA polymerase epsilon bound to DNA and PCNA (open conformation)
Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6E
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Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)
Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6F
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BU of 9f6f by Molmil
Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation)
Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6L
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BU of 9f6l by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Mismatch Excision state)
Descriptor: CALCIUM ION, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6J
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Human DNA Polymerase epsilon bound to T-C mismatched DNA (Polymerase Arrest state)
Descriptor: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024
9F6K
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BU of 9f6k by Molmil
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state)
Descriptor: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ...
Authors:Roske, J.J, Yeeles, J.T.P.
Deposit date:2024-05-01
Release date:2024-08-07
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Nat.Struct.Mol.Biol., 2024

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PDB entries from 2024-08-07

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