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PDB: 8 results

8B4J
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BU of 8b4j by Molmil
Rfa1-N-terminal domain in complex with phosphorylated Ddc2
Descriptor: 1,2-ETHANEDIOL, DNA damage checkpoint protein LCD1, Replication factor A protein 1, ...
Authors:Yates, L.A, Zhang, X.
Deposit date:2022-09-20
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:A DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A.
Proc.Natl.Acad.Sci.USA, 120, 2023
5OMD
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BU of 5omd by Molmil
Crystal structure of S. cerevisiae Ddc2 N-terminal coiled-coil domain
Descriptor: DNA damage checkpoint protein LCD1
Authors:Deshpande, I, Seeber, A, Shimada, K, Keusch, J.J, Gut, H, Gasser, S.M.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Mol. Cell, 68, 2017
6Z2W
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BU of 6z2w by Molmil
Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP
Descriptor: DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Yates, L.A, Zhang, X.
Deposit date:2020-05-18
Release date:2020-11-11
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
6Z2X
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BU of 6z2x by Molmil
Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP (State II)
Descriptor: DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Yates, L.A, Zhang, X.
Deposit date:2020-05-18
Release date:2020-11-11
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
6Z3A
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BU of 6z3a by Molmil
Mec1-Ddc2 (wild-type) in complex with AMP-PNP
Descriptor: DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ...
Authors:Yates, L.A, Zhang, X.
Deposit date:2020-05-19
Release date:2020-11-11
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
5X6O
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BU of 5x6o by Molmil
Intact ATR/Mec1-ATRIP/Ddc2 complex
Descriptor: DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1
Authors:Wang, X, Ran, T, Cai, G.
Deposit date:2017-02-22
Release date:2017-12-20
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:3.9 angstrom structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP.
Science, 358, 2017
7WZW
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BU of 7wzw by Molmil
Cryo-EM structure of MEC1-DDC2-MMS
Descriptor: DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1
Authors:Zhang, Q, Zhang, Q.
Deposit date:2022-02-19
Release date:2023-03-01
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins.
Cell Discov, 8, 2022
7WZR
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BU of 7wzr by Molmil
Cryo-EM structure of Mec1-HU
Descriptor: DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1
Authors:Zhang, Q, Zhang, Q.
Deposit date:2022-02-19
Release date:2023-03-08
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins.
Cell Discov, 8, 2022

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PDB entries from 2024-07-17

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