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PDB: 21 results

5NXQ
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BU of 5nxq by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP
Descriptor: DNA polymerase alpha-binding protein, GLYCEROL, MET-ASP-ILE-UA1-ILE-ASP-ASP-ILE-LEU-UA2-GLU-LEU-ASP-LYS-GLU
Authors:Wu, Y, Pellegrini, L.
Deposit date:2017-05-10
Release date:2017-08-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.
Angew. Chem. Int. Ed. Engl., 56, 2017
4C8H
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BU of 4c8h by Molmil
Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein.
Descriptor: CTF4
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase Alpha in the Eukaryotic Replisome
Nature, 510, 2014
4C93
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BU of 4c93 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha.
Descriptor: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A, DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C95
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BU of 4c95 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA REPLICATION COMPLEX GINS PROTEIN SLD5
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-02
Release date:2014-04-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C8S
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BU of 4c8s by Molmil
Crystal structure of the C-terminal region of yeast Ctf4
Descriptor: DNA POLYMERASE ALPHA-BINDING PROTEIN
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2013-10-01
Release date:2014-04-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
8KG6
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BU of 8kg6 by Molmil
Yeast replisome in state I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
Deposit date:2023-08-17
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
5HOG
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BU of 5hog by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
Descriptor: DNA polymerase alpha-binding protein, Dna2p
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.092 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
7PMK
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BU of 7pmk by Molmil
S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I)
Descriptor: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA helicase, ...
Authors:Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
Deposit date:2021-09-02
Release date:2021-11-10
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PMN
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BU of 7pmn by Molmil
S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II)
Descriptor: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha-binding protein, ...
Authors:Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
Deposit date:2021-09-02
Release date:2021-11-10
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
5HOI
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BU of 5hoi by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2.
Descriptor: DNA polymerase alpha-binding protein, Topoisomerase 1-associated factor 2
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
8B9B
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BU of 8b9b by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9A
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BU of 8b9a by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
Authors:Jones, M.L, Yeeles, J.T.P.
Deposit date:2022-10-05
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8XGC
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BU of 8xgc by Molmil
Structure of yeast replisome associated with FACT and histone hexamer, Composite map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
Authors:Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y.
Deposit date:2023-12-15
Release date:2024-02-14
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Parental histone transfer caught at the replication fork.
Nature, 627, 2024
6SKL
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BU of 6skl by Molmil
Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1
Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA fork, ...
Authors:Yeeles, J, Baretic, D, Jenkyn-Bedford, M.
Deposit date:2019-08-16
Release date:2020-05-06
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 78, 2020
6PTJ
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BU of 6ptj by Molmil
Structure of Ctf4 trimer in complex with one CMG helicase
Descriptor: Cell division control protein 45, DNA polymerase alpha-binding protein, DNA replication complex GINS protein PSF1, ...
Authors:Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
Deposit date:2019-07-15
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
8W7M
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BU of 8w7m by Molmil
Yeast replisome in state V
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (71-mer), ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
Deposit date:2023-08-30
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG8
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BU of 8kg8 by Molmil
Yeast replisome in state II
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
Deposit date:2023-08-17
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8KG9
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BU of 8kg9 by Molmil
Yeast replisome in state III
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
Deposit date:2023-08-17
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (4.52 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
6PTN
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BU of 6ptn by Molmil
Structure of Ctf4 trimer in complex with two CMG helicases
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
Authors:Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
Deposit date:2019-07-16
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
6PTO
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BU of 6pto by Molmil
Structure of Ctf4 trimer in complex with three CMG helicases
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
Authors:Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
Deposit date:2019-07-16
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
8W7S
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BU of 8w7s by Molmil
Yeast replisome in state IV
Descriptor: Cell division control protein 45, DNA (71-mer), DNA polymerase alpha-binding protein, ...
Authors:Dang, S, Zhai, Y, Feng, J, Yu, D.
Deposit date:2023-08-31
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (7.39 Å)
Cite:Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023

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PDB entries from 2024-08-21

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