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PDB: 323 results

6EEC
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BU of 6eec by Molmil
Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin
Descriptor: DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
Deposit date:2018-08-13
Release date:2018-11-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
6EDT
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BU of 6edt by Molmil
Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter
Descriptor: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
Deposit date:2018-08-10
Release date:2018-11-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY
Cite:Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
6EE8
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BU of 6ee8 by Molmil
Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter
Descriptor: DNA (60-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
Deposit date:2018-08-13
Release date:2018-11-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
6EYD
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BU of 6eyd by Molmil
Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Kouba, T, Barvik, I, Krasny, L.
Deposit date:2017-11-11
Release date:2018-12-12
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis.
J. Bacteriol., 201, 2019
6DVC
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BU of 6dvc by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6OMF
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BU of 6omf by Molmil
CryoEM structure of SigmaS-transcription initiation complex with activator Crl
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A.
Deposit date:2019-04-18
Release date:2019-08-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase.
Proc.Natl.Acad.Sci.USA, 116, 2019
6N60
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BU of 6n60 by Molmil
Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A.
Deposit date:2018-11-23
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6DVD
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BU of 6dvd by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position "-11
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*A)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.899 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6DVB
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BU of 6dvb by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer
Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lin, W, Das, K, Feng, Y, Ebright, R.H.
Deposit date:2018-06-23
Release date:2019-02-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6OVY
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BU of 6ovy by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-08
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OY7
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BU of 6oy7 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-14
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OUL
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BU of 6oul by Molmil
Cryo-EM structure of Escherichia coli RNAP polymerase bound to rpsTP2 promoter DNA
Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-05-04
Release date:2020-02-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
6OY5
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BU of 6oy5 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min
Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-14
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6FBV
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BU of 6fbv by Molmil
Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Das, K, Lin, W, Ebright, E.
Deposit date:2017-12-19
Release date:2018-02-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Mol. Cell, 70, 2018
6P1K
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BU of 6p1k by Molmil
Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-05-20
Release date:2020-02-26
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
6OVR
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BU of 6ovr by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1G
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*GP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-08
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.843 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OW3
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BU of 6ow3 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1T
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*TP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-09
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.766 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OY6
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BU of 6oy6 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-14
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.096 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6PMJ
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BU of 6pmj by Molmil
Sigm28-transcription initiation complex with specific promoter at the state 2
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Liu, B, Shi, W.
Deposit date:2019-07-02
Release date:2020-05-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Structural basis of bacterial sigma28-mediated transcription reveals roles of the RNA polymerase zinc-binding domain.
Embo J., 39, 2020
6P18
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BU of 6p18 by Molmil
Q21 transcription antitermination complex: loading complex
Descriptor: DNA (67-MER) fragment carrying phage-21 pR' promoter and pause element, nontemplate strand, template strand, ...
Authors:Yin, Z, Ebright, R.H.
Deposit date:2019-05-19
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of Q-dependent antitermination.
Proc.Natl.Acad.Sci.USA, 116, 2019
6P70
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BU of 6p70 by Molmil
X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-06-04
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
5VSW
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BU of 5vsw by Molmil
X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murakami, K.S, Molodtsov, V.
Deposit date:2017-05-12
Release date:2017-06-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4.295 Å)
Cite:Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA.
Mol. Cell, 69, 2018
5VI8
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BU of 5vi8 by Molmil
Structure of a mycobacterium smegmatis transcription initiation complex with an upstream-fork promoter fragment
Descriptor: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
Authors:Hubin, E.A, Campbell, E.A, Darst, S.A.
Deposit date:2017-04-14
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Nat Commun, 8, 2017
5VOI
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BU of 5voi by Molmil
X-ray crystal structure of bacterial RNA polymerase and pyrG promoter complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V.
Deposit date:2017-05-02
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W1S
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BU of 5w1s by Molmil
X-ray crystal structure of Escherichia coli RNA polymerase and TraR complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murakami, K.S, Molodtsov, V.
Deposit date:2017-06-04
Release date:2017-06-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.805 Å)
Cite:Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA.
Mol. Cell, 69, 2018

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