4UP0
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![BU of 4up0 by Molmil](/molmil-images/mine/4up0) | Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide | Descriptor: | HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... | Authors: | Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. | Deposit date: | 2014-06-11 | Release date: | 2014-11-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9, 2014
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1WEP
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![BU of 1wep by Molmil](/molmil-images/mine/1wep) | Solution structure of PHD domain in PHF8 | Descriptor: | PHF8, ZINC ION | Authors: | He, F, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-25 | Release date: | 2004-11-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of PHD domain in protein AA017385 To be Published
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5I3L
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![BU of 5i3l by Molmil](/molmil-images/mine/5i3l) | DPF3b in complex with H3K14ac peptide | Descriptor: | 1,2-ETHANEDIOL, H3K14ac peptide, SODIUM ION, ... | Authors: | Tempel, W, Liu, Y, Walker, J.R, Zhao, A, Qin, S, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2016-02-10 | Release date: | 2016-02-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of DPF3b in complex with an acetylated histone peptide. J.Struct.Biol., 195, 2016
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4L7X
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![BU of 4l7x by Molmil](/molmil-images/mine/4l7x) | |
6OIE
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![BU of 6oie by Molmil](/molmil-images/mine/6oie) | |
2RO1
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![BU of 2ro1 by Molmil](/molmil-images/mine/2ro1) | NMR Solution Structures of Human KAP1 PHD finger-bromodomain | Descriptor: | Transcription intermediary factor 1-beta, ZINC ION | Authors: | Zeng, L, Yap, K.L, Ivanov, A.V, Wang, X, Mujtaba, S, Plotnikova, O, Rauscher, F.J. | Deposit date: | 2008-03-04 | Release date: | 2008-05-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing Nat.Struct.Mol.Biol., 15, 2008
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5WLE
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![BU of 5wle by Molmil](/molmil-images/mine/5wle) | |
5WLF
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![BU of 5wlf by Molmil](/molmil-images/mine/5wlf) | |
1F62
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![BU of 1f62 by Molmil](/molmil-images/mine/1f62) | WSTF-PHD | Descriptor: | TRANSCRIPTION FACTOR WSTF, ZINC ION | Authors: | Pascual, J, Martinez-Yamout, M, Dyson, H.J, Wright, P.E. | Deposit date: | 2000-06-19 | Release date: | 2000-12-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor. J.Mol.Biol., 304, 2000
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1FP0
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![BU of 1fp0 by Molmil](/molmil-images/mine/1fp0) | SOLUTION STRUCTURE OF THE PHD DOMAIN FROM THE KAP-1 COREPRESSOR | Descriptor: | KAP-1 COREPRESSOR, ZINC ION | Authors: | Capili, A.D, Schultz, D.C, Rauscher III, F.J, Borden, K.L.B. | Deposit date: | 2000-08-29 | Release date: | 2001-01-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains. EMBO J., 20, 2001
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6VFO
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![BU of 6vfo by Molmil](/molmil-images/mine/6vfo) | Solution structure of the PHD of mouse UHRF1 (NP95) | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | Authors: | Lemak, A, Houliston, S, Duan, S, Arrowsmith, C.H. | Deposit date: | 2020-01-06 | Release date: | 2020-06-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. Nucleic Acids Res., 48, 2020
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7CWH
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![BU of 7cwh by Molmil](/molmil-images/mine/7cwh) | Structural basis of RACK7 PHD to read a pediatric glioblastoma-associated histone mutation H3.3G34R | Descriptor: | Peptide from Histone H3.3, Protein kinase C-binding protein 1, ZINC ION | Authors: | Lan, W.X, Li, Z, Jiao, F.F, Wang, C.X, Guo, R, Cao, C.Y. | Deposit date: | 2020-08-28 | Release date: | 2021-05-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of RACK7 PHD domain to read a pediatric glioblastoma‐associated histone mutation H3.3G34R Chin.J.Chem., 2021
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3ZVZ
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![BU of 3zvz by Molmil](/molmil-images/mine/3zvz) | PHD finger of human UHRF1 | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE UHRF1, ZINC ION | Authors: | Lallous, N, Birck, C, Mc Ewen, A.G, Legrand, P, Samama, J.P. | Deposit date: | 2011-07-28 | Release date: | 2011-11-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | The Phd Finger of Human Uhrf1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers. Plos One, 6, 2011
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3ZVY
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![BU of 3zvy by Molmil](/molmil-images/mine/3zvy) | PHD finger of human UHRF1 in complex with unmodified histone H3 N- terminal tail | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE UHRF1, ... | Authors: | Lallous, N, Birck, C, Mc Ewen, A.G, Legrand, P, Samama, J.P. | Deposit date: | 2011-07-28 | Release date: | 2011-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Phd Finger of Human Uhrf1 Reveals a New Subgroup of Unmethylated Histone H3 Tail Readers. Plos One, 6, 2011
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1MM3
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![BU of 1mm3 by Molmil](/molmil-images/mine/1mm3) | Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF | Descriptor: | Mi2-beta(Chromodomain helicase-DNA-binding protein 4) and transcription factor WSTF, ZINC ION | Authors: | Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2002-09-02 | Release date: | 2003-07-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
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1MM2
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![BU of 1mm2 by Molmil](/molmil-images/mine/1mm2) | Solution structure of the 2nd PHD domain from Mi2b | Descriptor: | Mi2-beta, ZINC ION | Authors: | Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2002-09-02 | Release date: | 2003-07-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
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6LSB
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![BU of 6lsb by Molmil](/molmil-images/mine/6lsb) | |
7KLO
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![BU of 7klo by Molmil](/molmil-images/mine/7klo) | |
7KLR
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7M10
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![BU of 7m10 by Molmil](/molmil-images/mine/7m10) | PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1 | Descriptor: | FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ... | Authors: | Horton, J.R, Cheng, X. | Deposit date: | 2021-03-11 | Release date: | 2021-05-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions. Biochem.J., 478, 2021
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2YSM
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![BU of 2ysm by Molmil](/molmil-images/mine/2ysm) | |
2YT5
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![BU of 2yt5 by Molmil](/molmil-images/mine/2yt5) | Solution structure of the PHD domain of Metal-response element-binding transcription factor 2 | Descriptor: | Metal-response element-binding transcription factor 2, ZINC ION | Authors: | Masuda, K, Muto, Y, Isono, K, Watanabe, S, Harada, T, Kigawa, T, Koseki, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2008-04-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the PHD domain of Metal-response element-binding transcription factor 2 To be Published
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4LJN
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![BU of 4ljn by Molmil](/molmil-images/mine/4ljn) | Crystal Structure of MOZ double PHD finger | Descriptor: | Histone acetyltransferase KAT6A, ZINC ION | Authors: | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | Deposit date: | 2013-07-05 | Release date: | 2013-10-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
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4LK9
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![BU of 4lk9 by Molmil](/molmil-images/mine/4lk9) | Crystal Structure of MOZ double PHD finger histone H3 tail complex | Descriptor: | Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION | Authors: | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | Deposit date: | 2013-07-07 | Release date: | 2013-10-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
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4LLB
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![BU of 4llb by Molmil](/molmil-images/mine/4llb) | Crystal Structure of MOZ double PHD finger histone H3K14ac complex | Descriptor: | Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION | Authors: | Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. | Deposit date: | 2013-07-09 | Release date: | 2013-10-16 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
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