7KLR

Solution structure of the PHD1 domain of histone demethylase KDM5A in complex with a histone H3(1-10) peptide

Summary for 7KLR

• Entry DOI: 10.2210/pdb7klr/pdb
• Related: 7KLO
• NMR Information: BMRB: 30809
• Descriptor: Lysine-specific demethylase 5A, Histone H3.1, ZINC ION (3 entities in total)
• Functional Keywords: phd, h3, epigenetics, kdm5a, gene regulation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 7886.71

Authors

Longbotham, E.J.,Kelly, M.J.S.,Fujimori, D.G. (deposition date: 2020-10-31, release date: 2021-03-03)

• Primary citation: Longbotham, J.E.,Kelly, M.J.S.,Fujimori, D.G.; Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A.; Acs Chem.Biol., 2021; PubMed: 33621062; DOI: 10.1021/acschembio.0c00976

Experimental method

SOLUTION NMR