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PDB: 82 results

1LGL
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Solution structure of HERG-specific scorpion toxin BeKm-1
Descriptor: BeKm-1 toxin
Authors:Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V.
Deposit date:2002-04-16
Release date:2002-11-20
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
J.Biol.Chem., 277, 2002
6SAB
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M-BUTX-Ptr1a (Parabuthus transvaalicus)
Descriptor: M-BUTX-Ptr1a
Authors:Meudal, H, Landon, C, Delmas, A.F.
Deposit date:2019-07-16
Release date:2020-07-22
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
J.Med.Chem., 63, 2020
3E8Y
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Xray structure of scorpion toxin BmBKTx1
Descriptor: CHLORIDE ION, Potassium channel toxin alpha-KTx 19.1, SULFATE ION
Authors:Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H.
Deposit date:2008-08-20
Release date:2009-02-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.
J.Am.Chem.Soc., 131, 2009
6VNZ
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NMR solution structure of tamapin, mutant K20A
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Mayorga Flores, M.
Deposit date:2020-01-29
Release date:2020-07-29
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells.
Acs Med.Chem.Lett., 11, 2020
6MZT
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Solution structure of alpha-KTx-6.21 (UroTx) from Urodacus yaschenkoi
Descriptor: Potassium channel toxin alpha-KTx 6.21
Authors:Chin, Y.K.-Y, Luna-Ramirez, K, Anangi, R, King, G.F.
Deposit date:2018-11-05
Release date:2020-03-11
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom.
Biochem. Pharmacol., 174, 2020
3ODV
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X-ray structure of kaliotoxin by racemic protein crystallography
Descriptor: CITRIC ACID, Potassium channel toxin alpha-KTx 3.1, trifluoroacetic acid
Authors:Pentelute, B.L, Mandal, K, Gates, Z.P, Sawaya, M.R, Yeates, T.O, Kent, S.B.H.
Deposit date:2010-08-11
Release date:2010-10-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.
Chem.Commun.(Camb.), 46, 2010
2RTZ
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Solution structure of MarkTX-7
Descriptor: Potassium channel blocker MarkTX-7
Authors:Umetsu, Y, Ohki, S.
Deposit date:2013-10-17
Release date:2014-10-22
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure of MarkTX-7
To be Published
2UVS
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High Resolution Solid-state NMR structure of Kaliotoxin
Descriptor: POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.1
Authors:Korukottu, J, Lange, A, Vijayan, V, Schneider, R, Pongs, O, Becker, S, Baldus, M, Zweckstetter, M.
Deposit date:2007-03-14
Release date:2008-05-27
Last modified:2024-11-06
Method:SOLID-STATE NMR
Cite:Conformational Plasticity in Ion Channel Recognition of a Peptide Toxin
To be Published
2PTA
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PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES
Descriptor: PANDINUS TOXIN K-ALPHA
Authors:Tenenholz, T.C, Rogowski, R.S, Collins, J.H, Blaustein, M.P, Weber, D.J.
Deposit date:1996-11-26
Release date:1997-12-10
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels.
Biochemistry, 36, 1997
6D3T
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NMR solution structure of tamapin, mutant DP30
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G, Mayorga Flores, M.
Deposit date:2018-04-16
Release date:2019-07-17
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D8H
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NMR solution structure of tamapin, mutant Y31+N
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:2018-04-26
Release date:2019-05-01
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D8T
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NMR solution structure of tamapin, mutant E25K/K27E
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:2018-04-26
Release date:2019-05-01
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
6D9O
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NMR solution structure of tamapin, mutant E25A
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:2018-04-30
Release date:2019-05-08
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
1J5J
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Solution structure of HERG-specific scorpion toxin BeKm-1
Descriptor: BeKm-1 toxin
Authors:Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V.
Deposit date:2002-04-16
Release date:2002-11-20
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
J.Biol.Chem., 277, 2002
1MTX
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DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF MARGATOXIN BY 1H, 13C, 15N TRIPLE-RESONANCE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: MARGATOXIN
Authors:Johnson, B.A, Stevens, S.P, Williamson, J.M.
Deposit date:1994-12-27
Release date:1995-11-14
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Determination of the three-dimensional structure of margatoxin by 1H, 13C, 15N triple-resonance nuclear magnetic resonance spectroscopy.
Biochemistry, 33, 1994
1M2S
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Solution Structure of A New Potassium Channels Blocker from the Venom of Chinese Scorpion Buthus martensi Karsch
Descriptor: Toxin BmTX3
Authors:Wang, Y, Li, M, Zhang, N, Wu, G, Hu, G, Wu, H.
Deposit date:2002-06-25
Release date:2004-04-06
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:The solution structure of BmTx3B, a member of the scorpion toxin subfamily alpha-KTx 16
Proteins, 58, 2005
1HP2
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SOLUTION STRUCTURE OF A TOXIN FROM THE SCORPION TITYUS SERRULATUS (TSTX-K ALPHA) DETERMINED BY NMR.
Descriptor: TITYUSTOXIN K ALPHA
Authors:Ellis, K.C, Tenenholz, T.C, Gilly, W.F, Blaustein, M.P, Weber, D.J.
Deposit date:2000-12-12
Release date:2001-06-13
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Interaction of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (sqKv1A).
Biochemistry, 40, 2001
1N8M
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Solution structure of Pi4, a four disulfide bridged scorpion toxin active on potassium channels
Descriptor: Potassium channel blocking toxin 4
Authors:Guijarro, J.I, M'Barek, S, Olamendi-Portugal, T, Gomez-Lagunas, F, Garnier, D, Rochat, H, Possani, L.D, Sabatier, J.M, Delepierre, M.
Deposit date:2002-11-21
Release date:2003-09-02
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels.
Protein Sci., 12, 2003
1HLY
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BU of 1hly by Molmil
SOLUTION STRUCTURE OF HONGOTOXIN 1
Descriptor: HONGOTOXIN 1
Authors:Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G.
Deposit date:2000-12-04
Release date:2003-09-30
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The first high affinity fluorescence probes for voltage-gated K+ channels.
BIOCONJUG.CHEM., 13, 2002
1Q2K
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Solution structure of BmBKTx1 a new potassium channel blocker from the Chinese Scorpion Buthus martensi Karsch
Descriptor: Neurotoxin BmK37
Authors:Cai, Z, Xu, C, Xu, Y, Lu, W, Chi, C.W, Shi, Y, Wu, J.
Deposit date:2003-07-25
Release date:2003-09-09
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Solution Structure of BmBKTx1, a New BK(Ca)(1) Channel Blocker from the Chinese Scorpion Buthus martensi Karsch(,).
Biochemistry, 43, 2004
1PNH
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SOLUTION STRUCTURE OF PO5-NH2, A SCORPION TOXIN ANALOG WITH HIGH AFFINITY FOR THE APAMIN-SENSITIVE POTASSIUM CHANNEL
Descriptor: SCORPION TOXIN
Authors:Meunier, S, Bernassau, J.-M, Sabatier, J.-M, Martin-Eauclaire, M.-F, Van Rietschoten, J, Cambillau, C, Darbon, H.
Deposit date:1993-08-25
Release date:1994-01-31
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure of P05-NH2, a scorpion toxin analog with high affinity for the apamin-sensitive potassium channel.
Biochemistry, 32, 1993
1KTX
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KALIOTOXIN (1-37) SHOWS STRUCTURAL DIFFERENCES WITH RELATED POTASSIUM CHANNEL BLOCKERS
Descriptor: KALIOTOXIN
Authors:Fernandez, I, Romi, R, Szendefi, S, Martin-Eauclaire, M.-F, Rochat, H, Van Rietschtoten, J, Pons, M, Giralt, E.
Deposit date:1994-06-02
Release date:1995-01-26
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Kaliotoxin (1-37) shows structural differences with related potassium channel blockers.
Biochemistry, 33, 1994
1LIR
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LQ2 FROM LEIURUS QUINQUESTRIATUS, NMR, 22 STRUCTURES
Descriptor: LQ2
Authors:Renisio, J.G, Lu, Z, Blanc, E, Jin, W, Lewis, J.H, Bornet, O, Darbon, H.
Deposit date:1998-04-02
Release date:1998-06-17
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Solution structure of potassium channel-inhibiting scorpion toxin Lq2.
Proteins, 34, 1999
1WPD
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Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
Descriptor: Potassium channel toxin alpha-KTx 6.2,Potassium channel toxin alpha-KTx 6.3
Authors:Regaya, I, Beeton, C, Ferrat, G, Andreotti, N, Chandy, G.K, Darbon, H, De Waard, M, Sabatier, J.M.
Deposit date:2004-09-01
Release date:2004-10-19
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
J.Biol.Chem., 279, 2004
1WZ5
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Solution structure of Pi1-3p
Descriptor: Potassium channel blocking toxin 1
Authors:Ferrat, G.
Deposit date:2005-02-24
Release date:2005-04-19
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily
Proteins, 61, 2005

 

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