4X9P
 
 | | Crystal structure of bovine Annexin A2 | | Descriptor: | Annexin A2, CALCIUM ION, CHLORIDE ION | | Authors: | Shumilin, I.A, Hollas, H, Vedeler, A, Kretsinger, R.H. | | Deposit date: | 2014-12-11 | | Release date: | 2015-01-14 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects.
Biochem. Pharmacol., 95, 2015
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8W5S
 | | Crystal structure of Annexin A7 mutant | | Descriptor: | Annexin A7, CALCIUM ION | | Authors: | Hua, Z.C, Tang, W. | | Deposit date: | 2023-08-27 | | Release date: | 2024-09-11 | | Method: | X-RAY DIFFRACTION (2.1162 Å) | | Cite: | structure dissection of the membrane aggregation mechanism induced by Annexin A7 mutation
To Be Published
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6B3I
 | | Annexin A13a | | Descriptor: | 1,2-ETHANEDIOL, Annexin | | Authors: | McCulloch, K.M, Iverson, T.M. | | Deposit date: | 2017-09-21 | | Release date: | 2018-10-10 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | An alternative N-terminal fold of the intestine-specific annexin A13a induces dimerization and regulates membrane-binding.
J. Biol. Chem., 294, 2019
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1SAV
 | | HUMAN ANNEXIN V WITH PROLINE SUBSTITUTION BY THIOPROLINE | | Descriptor: | ANNEXIN V, CALCIUM ION | | Authors: | Medrano, F.J, Minks, C, Budisa, N, Huber, R. | | Deposit date: | 1997-11-24 | | Release date: | 1998-05-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins.
J.Mol.Biol., 223, 1992
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4MDV
 | | Crystal structure of calcium-bound annexin (Sm)1 | | Descriptor: | Annexin, CALCIUM ION | | Authors: | Hofmann, A. | | Deposit date: | 2013-08-23 | | Release date: | 2014-02-26 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
Febs J., 281, 2014
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6K25
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2XO2
 | | Human Annexin V with incorporated Methionine analogue Azidohomoalanine | | Descriptor: | ANNEXIN A5, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Debela, M, Merkel, L, Goettig, P, Budisa, N. | | Deposit date: | 2010-08-09 | | Release date: | 2011-08-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Non-Canonical Amino Acids for Click Chemistry Reactions Incorporated in Human Annexin V
To be Published
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2RAN
 | | RAT ANNEXIN V CRYSTAL STRUCTURE: CA2+-INDUCED CONFORMATIONAL CHANGES | | Descriptor: | ANNEXIN V, CALCIUM ION, SULFATE ION | | Authors: | Concha, N.O, Head, J.F, Kaetzel, M.A, Dedman, J.R, Seaton, B.A. | | Deposit date: | 1994-09-01 | | Release date: | 1994-11-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Rat annexin V crystal structure: Ca(2+)-induced conformational changes.
Science, 261, 1993
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7ZVN
 | | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 1.87 A resolution | | Descriptor: | 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, CALCIUM ION, ... | | Authors: | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | | Deposit date: | 2022-05-16 | | Release date: | 2022-09-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Nucleic Acids Res., 51, 2023
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7ZVX
 | | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution | | Descriptor: | 1,2-ETHANEDIOL, 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, ... | | Authors: | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | | Deposit date: | 2022-05-17 | | Release date: | 2022-09-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Nucleic Acids Res., 51, 2023
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7DTO
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2Q4C
 | | Ensemble refinement of the protein crystal structure of annexin from Arabidopsis thaliana gene At1g35720 | | Descriptor: | Annexin D1 | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.508 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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7EQ7
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2XO3
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6K22
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4MDU
 | | Crystal structure of apo-Annexin (Sm)1 | | Descriptor: | Annexin | | Authors: | Hofmann, A. | | Deposit date: | 2013-08-23 | | Release date: | 2014-02-26 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure and immunological properties of the first annexin from Schistosoma mansoni: insights into the structural integrity of the schistosomal tegument.
Febs J., 281, 2014
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8H0J
 | | Annexin A5 mutant | | Descriptor: | Annexin A5, CALCIUM ION | | Authors: | Hua, Z.C, Tang, W. | | Deposit date: | 2022-09-29 | | Release date: | 2023-10-04 | | Last modified: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia.
Acta Pharmacol.Sin., 46, 2025
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8GYC
 | | Annexin A5 protein dimer mutant | | Descriptor: | Annexin A5, CALCIUM ION | | Authors: | Hua, Z.C, Tang, W. | | Deposit date: | 2022-09-22 | | Release date: | 2023-10-18 | | Last modified: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia.
Acta Pharmacol.Sin., 46, 2025
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2ZOC
 | | Crystal structure of recombinant human annexin IV | | Descriptor: | Annexin A4, CALCIUM ION | | Authors: | Konno, M, Kaneko-Kanzaki, Y, Fushinobu-Okushi, N, Mochizuki, K, Uchikaw, E, Satoh, A, Aikawa, K. | | Deposit date: | 2008-05-08 | | Release date: | 2009-04-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The comparison of the loop structure of membrane binding sites between human and bovine annexin IV
To be Published
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2ZHJ
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2ZHI
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9GA8
 | | The crystal structure of human Annexin A4 from crystals grown at 4 mM Calcium | | Descriptor: | Annexin A4, CALCIUM ION, SULFATE ION | | Authors: | Ruggiero, A, Barra, G, Ghilardi, O, Scala, M.C, Sala, M, Di Micco, S, Bifulco, G, Campiglia, P, Vitagliano, L. | | Deposit date: | 2024-07-26 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Computational, crystallographic, and biophysical characterizations provide insights into calcium and phosphate binding by human annexin A4.
Int.J.Biol.Macromol., 308, 2025
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9GA7
 | | The crystal structure of human Annexin A4 derived from crystal grown at 4 mM CaCl2 and retro-soaking | | Descriptor: | Annexin A4, CALCIUM ION, SULFATE ION | | Authors: | Vitagliano, L, Barra, G, Ghilardi, O, Di Micco, S, Scala, M.C, Sala, M, Campiglia, P, Bifulco, G, Ruggiero, A. | | Deposit date: | 2024-07-26 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.446 Å) | | Cite: | Computational, crystallographic, and biophysical characterizations provide insights into calcium and phosphate binding by human annexin A4.
Int.J.Biol.Macromol., 308, 2025
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9GA6
 | | The crystal structure of human Annexin A4 derived from crystals grown in 40 mM of CaCl2 | | Descriptor: | Annexin A4, CALCIUM ION, GLYCEROL, ... | | Authors: | Vitagliano, L, Barra, G, Ghilardi, O, Di Micco, S, Bifulco, G, Campiglia, P, Sala, M, Scala, M.C, Ruggiero, A. | | Deposit date: | 2024-07-26 | | Release date: | 2025-06-04 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Computational, crystallographic, and biophysical characterizations provide insights into calcium and phosphate binding by human annexin A4.
Int.J.Biol.Macromol., 308, 2025
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8H9Z
 | | Annexin A5 protein mutant | | Descriptor: | Annexin A5, CALCIUM ION | | Authors: | Hua, Z.C, Tang, W. | | Deposit date: | 2022-10-26 | | Release date: | 2023-11-01 | | Last modified: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia.
Acta Pharmacol.Sin., 46, 2025
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