5VU5
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![BU of 5vu5 by Molmil](/molmil-images/mine/5vu5) | TNA polymerase, apo | Descriptor: | DNA polymerase | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU7
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![BU of 5vu7 by Molmil](/molmil-images/mine/5vu7) | TNA polymerase, open ternary complex | Descriptor: | 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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1Q9Y
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![BU of 1q9y by Molmil](/molmil-images/mine/1q9y) | CRYSTAL STRUCTURE OF ENTEROBACTERIA PHAGE RB69 GP43 DNA POLYMERASE COMPLEXED WITH 8-OXOGUANOSINE CONTAINING DNA | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-AC(8-OXOGUANOSINE)GGTAAGCAGTCCGCG-3', 5'-GCGGACTGCTTAC(DIDEOXYCYTIDINE)-3', ... | Authors: | Freisinger, E, Grollman, A.P, Miller, H, Kisker, C. | Deposit date: | 2003-08-26 | Release date: | 2004-04-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Lesion (in)tolerance reveals insights into DNA replication fidelity. Embo J., 23, 2004
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5VU9
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![BU of 5vu9 by Molmil](/molmil-images/mine/5vu9) | TNA polymerase, translocated product | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU8
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![BU of 5vu8 by Molmil](/molmil-images/mine/5vu8) | TNA polymerase, closed ternary complex | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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1QQC
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![BU of 1qqc by Molmil](/molmil-images/mine/1qqc) | CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK | Descriptor: | DNA POLYMERASE II, MAGNESIUM ION, SULFATE ION | Authors: | Zhao, Y, Jeruzalmi, D, Leighton, L, Lasken, R, Kuriyan, J. | Deposit date: | 1999-06-02 | Release date: | 1999-10-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of an archaebacterial DNA polymerase Structure Fold.Des., 7, 1999
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2P5G
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![BU of 2p5g by Molmil](/molmil-images/mine/2p5g) | Crystal structure of RB69 gp43 in complex with DNA with dAMP opposite an abasic site analog in a 21mer template | Descriptor: | DNA polymerase, Primer DNA, Template DNA | Authors: | Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. | Deposit date: | 2007-03-15 | Release date: | 2007-10-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
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5VU6
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![BU of 5vu6 by Molmil](/molmil-images/mine/5vu6) | |
2OYQ
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![BU of 2oyq by Molmil](/molmil-images/mine/2oyq) | Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog | Descriptor: | 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ... | Authors: | Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. | Deposit date: | 2007-02-22 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
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7B0H
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![BU of 7b0h by Molmil](/molmil-images/mine/7b0h) | TgoT_6G12 Ternary complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*GP*GP*CP*AP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ... | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-19 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B08
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![BU of 7b08 by Molmil](/molmil-images/mine/7b08) | TgoT apo | Descriptor: | DNA polymerase, THYMIDINE-5'-TRIPHOSPHATE, TRIETHYLENE GLYCOL | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.394 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B07
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![BU of 7b07 by Molmil](/molmil-images/mine/7b07) | TgoT_6G12 apo | Descriptor: | CALCIUM ION, DNA polymerase | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.099 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B0G
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![BU of 7b0g by Molmil](/molmil-images/mine/7b0g) | TgoT_6G12 binary with 2 hCTPs | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(P*AP*TP*TP*GP*GP*CP*TP*GP*CP*CP*CP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*GP*CP*AP*GP*()P*())-3'), ... | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-19 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B0F
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![BU of 7b0f by Molmil](/molmil-images/mine/7b0f) | TgoT_6G12 Binary complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*GP*GP*CP*TP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ... | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-19 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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7B06
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![BU of 7b06 by Molmil](/molmil-images/mine/7b06) | TgoT_RT521 apo | Descriptor: | DNA polymerase | Authors: | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | Deposit date: | 2020-11-18 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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8B9D
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![BU of 8b9d by Molmil](/molmil-images/mine/8b9d) | Human replisome bound by Pol Alpha | Descriptor: | Cell division control protein 45 homolog, Claspin, DNA Molecule, ... | Authors: | Jones, M.L, Yeeles, J.T.P. | Deposit date: | 2022-10-05 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
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1S5J
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![BU of 1s5j by Molmil](/molmil-images/mine/1s5j) | Insight in DNA Replication: The crystal structure of DNA Polymerase B1 from the archaeon Sulfolobus solfataricus | Descriptor: | DNA polymerase I, MAGNESIUM ION, SULFATE ION | Authors: | Savino, C, Federici, L, Nastopoulos, V, Johnson, K.A, Pisani, F.M, Rossi, M, Tsernoglou, D. | Deposit date: | 2004-01-21 | Release date: | 2004-11-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus Structure, 12, 2004
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8B9C
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![BU of 8b9c by Molmil](/molmil-images/mine/8b9c) | S. cerevisiae pol alpha - replisome complex | Descriptor: | Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... | Authors: | Jones, M.L, Yeeles, J.T.P. | Deposit date: | 2022-10-05 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
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8B9B
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![BU of 8b9b by Molmil](/molmil-images/mine/8b9b) | |
8B9A
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![BU of 8b9a by Molmil](/molmil-images/mine/8b9a) | |
8D0K
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![BU of 8d0k by Molmil](/molmil-images/mine/8d0k) | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | Authors: | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | Deposit date: | 2022-05-26 | Release date: | 2022-06-22 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (4.27 Å) | Cite: | Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022
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8D0B
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![BU of 8d0b by Molmil](/molmil-images/mine/8d0b) | Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template | Descriptor: | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... | Authors: | He, Q, Lin, X, Chavez, B.L, Agrawal, S, Lusk, B.L, Lim, C. | Deposit date: | 2022-05-26 | Release date: | 2022-06-22 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Nature, 608, 2022
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1TGO
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![BU of 1tgo by Molmil](/molmil-images/mine/1tgo) | THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS | Descriptor: | PROTEIN (THERMOSTABLE B DNA POLYMERASE) | Authors: | Hopfner, K.-P, Eichinger, A, Engh, R.A, Laue, F, Ankenbauer, W, Huber, R, Angerer, B. | Deposit date: | 1999-02-23 | Release date: | 1999-03-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc.Natl.Acad.Sci.USA, 96, 1999
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1WAF
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![BU of 1waf by Molmil](/molmil-images/mine/1waf) | DNA POLYMERASE FROM BACTERIOPHAGE RB69 | Descriptor: | DNA POLYMERASE, GUANOSINE | Authors: | Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A. | Deposit date: | 1997-04-13 | Release date: | 1998-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Cell(Cambridge,Mass.), 89, 1997
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1WAJ
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![BU of 1waj by Molmil](/molmil-images/mine/1waj) | DNA POLYMERASE FROM BACTERIOPHAGE RB69 | Descriptor: | DNA POLYMERASE, GUANOSINE-5'-MONOPHOSPHATE | Authors: | Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A. | Deposit date: | 1997-04-13 | Release date: | 1998-01-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Cell(Cambridge,Mass.), 89, 1997
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