3H7H
 
 | | Crystal structure of the human transcription elongation factor DSIF, hSpt4/hSpt5 (176-273) | | Descriptor: | BETA-MERCAPTOETHANOL, Transcription elongation factor SPT4, Transcription elongation factor SPT5, ... | | Authors: | Wenzel, S, Wohrl, B.M, Rosch, P, Martins, B.M. | | Deposit date: | 2009-04-27 | | Release date: | 2009-12-08 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface
Biochem.J., 425, 2010
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8UHD
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7UND
 | | Pol II-DSIF-SPT6-PAF1c-TFIIS-nucleosome complex (stalled at +38) | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... | | Authors: | Filipovski, M, Vos, S.M, Farnung, L. | | Deposit date: | 2022-04-10 | | Release date: | 2022-10-19 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of nucleosome retention during transcription elongation.
Science, 376, 2022
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6GMH
 | | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 | | Descriptor: | CDC73, CTR9,RNA polymerase-associated protein CTR9 homolog,RNA polymerase-associated protein CTR9 homolog, DNA-directed RNA polymerase II subunit RPB9, ... | | Authors: | Vos, S.M, Farnung, L, Boehing, M, Linden, A, Wigge, C, Urlaub, H, Cramer, P. | | Deposit date: | 2018-05-26 | | Release date: | 2018-08-22 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of activated transcription complex Pol II-DSIF-PAF-SPT6.
Nature, 560, 2018
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6TED
 | | Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | | Descriptor: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | | Authors: | Vos, S.M, Farnung, L, Cramer, P. | | Deposit date: | 2019-11-11 | | Release date: | 2020-07-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
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6GML
 | | Structure of paused transcription complex Pol II-DSIF-NELF | | Descriptor: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | | Deposit date: | 2018-05-27 | | Release date: | 2018-09-05 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
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8UHA
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8P4D
 | | Structural insights into human co-transcriptional capping - structure 4 | | Descriptor: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | | Authors: | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | | Deposit date: | 2023-05-20 | | Release date: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
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5OIK
 | | Structure of an RNA polymerase II-DSIF transcription elongation complex | | Descriptor: | DNA (43-MER), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | | Authors: | Bernecky, C, Plitzko, J.M, Cramer, P. | | Deposit date: | 2017-07-18 | | Release date: | 2017-09-13 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp.
Nat. Struct. Mol. Biol., 24, 2017
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8P4C
 | | Structural insights into human co-transcriptional capping - structure 3 | | Descriptor: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | | Authors: | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | | Deposit date: | 2023-05-20 | | Release date: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
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8W8E
 | | human co-transcriptional RNA capping enzyme RNGTT | | Descriptor: | DNA (36-MER), DNA (45-MER), DNA-directed RNA polymerase II subunit E, ... | | Authors: | Li, Y, Wang, Q, Xu, Y, Li, Z. | | Deposit date: | 2023-09-02 | | Release date: | 2024-04-10 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structures of co-transcriptional RNA capping enzymes on paused transcription complex.
Nat Commun, 15, 2024
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8W8F
 | | human co-transcriptional RNA capping enzyme RNGTT-CMTR1 | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (36-MER), DNA (45-MER), ... | | Authors: | Li, Y, Wang, Q, Xu, Y, Li, Z. | | Deposit date: | 2023-09-02 | | Release date: | 2024-04-10 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures of co-transcriptional RNA capping enzymes on paused transcription complex.
Nat Commun, 15, 2024
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8P4F
 | | Structural insights into human co-transcriptional capping - structure 6 | | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (38-MER), ... | | Authors: | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | | Deposit date: | 2023-05-20 | | Release date: | 2023-07-19 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
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7OKY
 | | Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P. | | Deposit date: | 2021-05-18 | | Release date: | 2021-07-14 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4.14 Å) | | Cite: | Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
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7YCX
 | | The structure of INTAC-PEC complex | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | | Authors: | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | | Deposit date: | 2022-07-02 | | Release date: | 2023-03-15 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | Structural basis of INTAC-regulated transcription.
Protein Cell, 14, 2023
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