7OB9
| Cryo-EM structure of human RNA Polymerase I in elongation state | Descriptor: | DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... | Authors: | Misiaszek, A.D, Girbig, M, Mueller, C.W. | Deposit date: | 2021-04-21 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
|
|
7AE1
| Cryo-EM structure of human RNA Polymerase III elongation complex 1 | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | Deposit date: | 2020-09-17 | Release date: | 2021-02-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
|
|
7VBB
| Structure of the post state human RNA Polymerase I Elongation Complex | Descriptor: | DNA (25-MER), DNA (5'-D(*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*CP*GP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ... | Authors: | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | Deposit date: | 2021-08-31 | Release date: | 2022-03-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Structure of the human RNA polymerase I elongation complex. Cell Discov, 7, 2021
|
|
7VBA
| Structure of the pre state human RNA Polymerase I Elongation Complex | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(P*A*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*AP*GP*AP*CP*AP*GP*CP*GP*AP*GP*TP*CP*AP*GP*CP*AP*A)-3'), ... | Authors: | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | Deposit date: | 2021-08-31 | Release date: | 2022-02-16 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure of the human RNA polymerase I elongation complex. Cell Discov, 7, 2021
|
|
7D58
| cryo-EM structure of human RNA polymerase III in elongating state | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | Deposit date: | 2020-09-25 | Release date: | 2021-02-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
|
|
7VBC
| Back track state of human RNA Polymerase I Elongation Complex | Descriptor: | DNA (5'-D(*GP*TP*AP*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*G)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*AP*GP*CP*GP*TP*GP*TP*CP*AP*GP*CP*AP*AP*TP*A)-3'), DNA-directed RNA polymerase I subunit RPA1, ... | Authors: | Zhao, D, Liu, W, Chen, K, Yang, H, Xu, Y. | Deposit date: | 2021-08-31 | Release date: | 2022-02-16 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structure of the human RNA polymerase I elongation complex. Cell Discov, 7, 2021
|
|
7AE3
| Cryo-EM structure of human RNA Polymerase III elongation complex 3 | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | Deposit date: | 2020-09-17 | Release date: | 2021-02-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
|
|
7OBA
| Cryo-EM structure of human RNA Polymerase I in complex with RRN3 | Descriptor: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | Authors: | Misiaszek, A.D, Girbig, M, Mueller, C.W. | Deposit date: | 2021-04-21 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
|
|
7D59
| cryo-EM structure of human RNA polymerase III in apo state | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | Deposit date: | 2020-09-25 | Release date: | 2021-02-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
|
|
7A6H
| Cryo-EM structure of human apo RNA Polymerase III | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | Deposit date: | 2020-08-25 | Release date: | 2021-02-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
|
|
7OBB
| Cryo-EM structure of human RNA Polymerase I Open Complex | Descriptor: | DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... | Authors: | Misiaszek, A.D, Girbig, M, Mueller, C.W. | Deposit date: | 2021-04-21 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
|
|
7DU2
| RNA polymerase III EC complex in post-translocation state | Descriptor: | DNA (5'-D(P*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*T)-3'), DNA-directed RNA polymerase III subunit RPC1, ... | Authors: | Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. | Deposit date: | 2021-01-07 | Release date: | 2021-03-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
|
|
8IUH
| RNA polymerase III pre-initiation complex open complex 1 | Descriptor: | DNA (81-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | Authors: | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | Deposit date: | 2023-03-24 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
|
|
7AEA
| Cryo-EM structure of human RNA Polymerase III elongation complex 2 | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | Deposit date: | 2020-09-17 | Release date: | 2021-02-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
|
|
7DN3
| Structure of Human RNA Polymerase III elongation complex | Descriptor: | DNA (5'-D(P*TP*CP*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*TP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase III subunit RPC1, ... | Authors: | Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. | Deposit date: | 2020-12-08 | Release date: | 2021-03-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
|
|
7FJI
| human Pol III elongation complex | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Hou, H, Xu, Y. | Deposit date: | 2021-08-04 | Release date: | 2021-10-27 | Last modified: | 2021-11-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
|
|
7FJJ
| human Pol III pre-termination complex | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Hou, H, Xu, Y. | Deposit date: | 2021-08-04 | Release date: | 2021-10-27 | Last modified: | 2021-11-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
|
|
8ITY
| human RNA polymerase III pre-initiation complex closed DNA 1 | Descriptor: | DNA (82-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | Authors: | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | Deposit date: | 2023-03-23 | Release date: | 2023-06-07 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
|
|
6DRD
| RNA Pol II(G) | Descriptor: | DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G. | Deposit date: | 2018-06-11 | Release date: | 2019-06-12 | Last modified: | 2019-12-04 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat. Struct. Mol. Biol., 25, 2018
|
|
5IYC
| Human core-PIC in the initial transcribing state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
5IYD
| Human core-PIC in the initial transcribing state (no IIS) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
5IYB
| Human core-PIC in the open state | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | Deposit date: | 2016-03-24 | Release date: | 2016-05-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
7AST
| Apo Human RNA Polymerase III | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A. | Deposit date: | 2020-10-28 | Release date: | 2020-12-23 | Last modified: | 2020-12-30 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of human RNA polymerase III. Nat Commun, 11, 2020
|
|
8A43
| Human RNA polymerase I | Descriptor: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | Authors: | Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C. | Deposit date: | 2022-06-10 | Release date: | 2022-08-31 | Last modified: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (4.09 Å) | Cite: | The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans. Life Sci Alliance, 5, 2022
|
|
8IUE
| RNA polymerase III pre-initiation complex melting complex 1 | Descriptor: | DNA (74-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | Authors: | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | Deposit date: | 2023-03-24 | Release date: | 2023-05-24 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
|
|