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PDB: 229 results

1K5N
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HLA-B*2709 BOUND TO NONA-PEPTIDE M9
Descriptor: GLYCEROL, beta-2-microglobulin, light chain, ...
Authors:Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2001-10-11
Release date:2002-10-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations
J.Biol.Chem., 277, 2002
4U1M
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BU of 4u1m by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
3CZF
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BU of 3czf by Molmil
Crystal structure of HLA-B*2709 complexed with the glucagon receptor (GR) peptide (residues 412-420)
Descriptor: BETA-2-MICROGLOBULIN, GLUCAGON RECEPTOR PEPTIDE, GLYCEROL, ...
Authors:Loll, B, Fiorillo, M.T, Rueckert, C, Saenger, W, Sorrentino, R, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2008-04-29
Release date:2009-04-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection.
Front Immunol, 11, 2020
6MT3
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BU of 6mt3 by Molmil
Crystal Structure of HLA-B*18:01 in complex with NP338 influenza peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-18 alpha chain, ...
Authors:Gras, S.
Deposit date:2018-10-19
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Broad CD8+T cell cross-recognition of distinct influenza A strains in humans.
Nat Commun, 9, 2018
3LN4
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BU of 3ln4 by Molmil
Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2
Descriptor: 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ...
Authors:Theodossis, A, Gras, S, Rossjohn, J.
Deposit date:2010-02-01
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.296 Å)
Cite:The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
3BWA
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Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein
Descriptor: Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
Authors:Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
Deposit date:2008-01-08
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
3SPV
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BU of 3spv by Molmil
Crystal structure of a peptide-HLA complex
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2011-07-04
Release date:2012-07-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of a peptide-HLA complex
To be Published
6MT6
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BU of 6mt6 by Molmil
Crystal Structure of HLA-B*37:01 in complex with NP338 influenza peptide
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S.
Deposit date:2018-10-19
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Broad CD8+T cell cross-recognition of distinct influenza A strains in humans.
Nat Commun, 9, 2018
6MTL
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BU of 6mtl by Molmil
Crystal Structure of HLA-B*44:05 in complex with NP338 influenza peptide
Descriptor: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ...
Authors:Gras, S.
Deposit date:2018-10-19
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Broad CD8+T cell cross-recognition of distinct influenza A strains in humans.
Nat Commun, 9, 2018
2BVP
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BU of 2bvp by Molmil
Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression
Descriptor: BETA-2-MICROGLOBULIN, HIV-P24, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y.
Deposit date:2005-07-01
Release date:2005-09-07
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
J Immunol., 175, 2005
4U1J
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BU of 4u1j by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
6PYW
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BU of 6pyw by Molmil
Crystal Structure of HLA-B*2705-W60A in complex with LRN, a self-peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ...
Authors:Gras, S.
Deposit date:2019-07-31
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
6P2C
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BU of 6p2c by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
Authors:Li, L, Batliwala, M, Bouvier, M.
Deposit date:2019-05-21
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.396 Å)
Cite:ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
4QRT
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BU of 4qrt by Molmil
Crystal Structure of HLA B*0801 in complex with ELN_YYM, ELNRKMIYM
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Twist, K.-A, Rossjohn, J.
Deposit date:2014-07-02
Release date:2014-07-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
4QRS
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BU of 4qrs by Molmil
Crystal Structure of HLA B*0801 in complex with ELK_IYM, ELKRKMIYM
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Twist, K.-A, Rossjohn, J.
Deposit date:2014-07-02
Release date:2014-12-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
5WMQ
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BU of 5wmq by Molmil
Crystal Structure of HLA-B8 in complex with ELR, an Influenza A virus peptide
Descriptor: Beta-2-microglobulin, ELR peptide from IAV, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-07-31
Release date:2018-06-06
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
2A83
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BU of 2a83 by Molmil
Crystal structure of hla-b*2705 complexed with the glucagon receptor (gr) peptide (residues 412-420)
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Ruckert, C, Fiorillo, M.T, Loll, B, Moretti, R, Biesiadka, J, Saenger, W, Ziegler, A, Sorrentino, R, Uchanska-Ziegler, B.
Deposit date:2005-07-07
Release date:2005-12-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype.
J.Biol.Chem., 281, 2006
4XXC
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HLA-B*1801 in complex with a self-peptide, DELEIKAY
Descriptor: ACETATE ION, ASP-GLU-LEU-GLU-ILE-LYS-ALA-TYR, Beta-2-microglobulin, ...
Authors:Hibbert, K.M, Rossjohn, J, Gras, S.
Deposit date:2015-01-30
Release date:2015-04-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.426 Å)
Cite:T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells.
J Immunol., 194, 2015
5IB2
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BU of 5ib2 by Molmil
Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B.
Deposit date:2016-02-22
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
6PYV
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BU of 6pyv by Molmil
Crystal Structure of HLA-B*2703-P47G in complex with LRN, a self-peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-2703 alpha chain, ...
Authors:Gras, S.
Deposit date:2019-07-31
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
6BXP
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BU of 6bxp by Molmil
Crystal Structure of HLA-B*57:01 with a modified HIV peptide RKV-Kyn
Descriptor: ACETATE ION, Beta-2-microglobulin, HIV peptide RKV-Kyn, ...
Authors:Gras, S, Rossjohn, J.
Deposit date:2017-12-18
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics.
Proteomics, 18, 2018
1OGT
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BU of 1ogt by Molmil
CRYSTAL STRUCTURE OF HLA-B*2705 COMPLEXED WITH THE VASOACTIVE INTESTINAL PEPTIDE TYPE 1 RECEPTOR (VIPR) PEPTIDE (RESIDUES 400-408)
Descriptor: BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Hulsmeyer, M, Fiorillo, M.T, Bettosini, F, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2003-05-13
Release date:2004-01-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Dual, HLA-B27 subtype-dependent conformation of a self-peptide.
J. Exp. Med., 199, 2004
1XH3
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BU of 1xh3 by Molmil
Conformational Restraints and Flexibility of 14-Meric Peptides in Complex with HLA-B*3501
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Probst-Kepper, M, Hecht, H.J, Herrmann, H, Janke, V, Ocklenburg, F, Klempnauer, J, van den Eynde, B.J, Weiss, S.
Deposit date:2004-09-17
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501.
J.Immunol., 173, 2004
6P2F
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Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
Authors:Li, L, Batliwala, M, Bouvier, M.
Deposit date:2019-05-21
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6AT5
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BU of 6at5 by Molmil
Crystal structure of HLA-B*07:02 in complex with an NY-ESO-1 peptide
Descriptor: Beta-2-microglobulin, Cancer/testis antigen 1 peptide, HLA class I histocompatibility antigen, ...
Authors:Gully, B.S, Rossjohn, J.
Deposit date:2017-08-27
Release date:2018-02-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Nat Commun, 9, 2018

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