5IB2

Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR

Summary for 5IB2

• Entry DOI: 10.2210/pdb5ib2/pdb
• Descriptor: HLA class I histocompatibility antigen, B-27 alpha chain, Beta-2-microglobulin, Vasoactive intestinal polypeptide receptor 1, ... (5 entities in total)
• Functional Keywords: immune system-complex, immune system, mhc major histocompatibility complex, hla- b*2705
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 45575.59

Authors

Janke, R.,Ballaschk, M.,Schmieder, P.,Uchanska-Ziegler, B.,Ziegler, A.,Loll, B. (deposition date: 2016-02-22, release date: 2017-02-01, Last modification date: 2024-01-10)

• Primary citation: Driller, R.,Ballaschk, M.,Schmieder, P.,Uchanska-Ziegler, B.,Ziegler, A.,Loll, B.; Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.; J.Biol.Chem., 2019; PubMed: 31296658; DOI: 10.1074/jbc.RA119.008937

Experimental method

X-RAY DIFFRACTION (1.44 Å)