8YN3
| Cryo-EM structure of histamine H2 receptor in complex with histamine and miniGs | Descriptor: | CHOLESTEROL, Engineered guanine nucleotide,binding protein G(s) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, Liu, G, Li, X, Gong, W. | Deposit date: | 2024-03-10 | Release date: | 2024-10-09 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Structural basis of ligand recognition and activation of the histamine receptor family. Nat Commun, 15, 2024
|
|
8YUT
| Cryo-EM structure of the amthamine-bound H2R-Gs complex | Descriptor: | 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | Deposit date: | 2024-03-27 | Release date: | 2024-06-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs. Adv Sci, 11, 2024
|
|
8YN4
| Cryo-EM structure of histamine H2 receptor in complex with histamine and miniGq | Descriptor: | Antibody fragment scFv16, CHOLESTEROL, Engineered guanine nucleotide-binding protein G(q) subunit alpha, ... | Authors: | Zhang, X, Liu, G, Li, X, Gong, W. | Deposit date: | 2024-03-10 | Release date: | 2024-10-09 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structural basis of ligand recognition and activation of the histamine receptor family. Nat Commun, 15, 2024
|
|
7UL3
| CryoEM Structure of Inactive H2R Bound to Famotidine, Nb6M, and NabFab | Descriptor: | Histamine H2 receptor, NabFab HC, NabFab LC, ... | Authors: | Robertson, M.J, Skiniotis, G. | Deposit date: | 2022-04-03 | Release date: | 2022-06-29 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure determination of inactive-state GPCRs with a universal nanobody. Nat.Struct.Mol.Biol., 29, 2022
|
|
8POK
| Cryo-EM structure of cell-free synthesized human histamine H2 receptor coupled to heterotrimeric Gs protein in lipid environment | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, HISTAMINE, ... | Authors: | Schnelle, K, Koeck, Z, Persechino, M, Umbach, S, Schihada, H, Januliene, D, Parey, K, Pockes, S, Kolb, P, Doetsch, V, Moeller, A, Hilger, D, Bernhard, F. | Deposit date: | 2023-07-05 | Release date: | 2024-03-06 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment. Nat Commun, 15, 2024
|
|