4BK7
 
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4BKD
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4MNS
 | | Crystal structure of the major pollen allergen Bet v 1-A in complex with P303 | | Descriptor: | (3R,4R,5aR,11aR)-3-methyl-6,11-dioxo-2,3,4,5,5a,6,11,11a-octahydrothiepino[3,2-g]isoquinoline-4-carboxylic acid, Major pollen allergen Bet v 1-A | | Authors: | Leone, P, Roussel, A. | | Deposit date: | 2013-09-11 | | Release date: | 2015-03-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Development and evaluation of a sublingual tablet based on recombinant Bet v 1 in birch pollen-allergic patients.
Allergy, 70, 2015
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4A87
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4A85
 | | Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in complex with kinetin. | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAJOR POLLEN ALLERGEN BET V 1-A, ... | | Authors: | Kofler, S, Brandstetter, H. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
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4BTZ
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4A84
 | | Crystal Structure of Major Birch Pollen Allergen Bet v 1 a F30V mutant in complex with deoxycholate. | | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR POLLEN ALLERGEN BET V 1-A, ... | | Authors: | Kofler, S, Brandstetter, H. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
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4A88
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4A83
 | | Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in complex with deoxycholate. | | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR POLLEN ALLERGEN BET V 1-A, ... | | Authors: | Kofler, S, Brandstetter, H. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
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4A86
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4BK6
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4BKC
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4B9R
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4A80
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1BV1
 | | BIRCH POLLEN ALLERGEN BET V 1 | | Descriptor: | BET V 1 | | Authors: | Gajhede, M, Osmark, P, Poulsen, F.M, Ipsen, H, Larson, J.N, Joostvan, R.J, Schou, C, Lowenstein, H, Spangfort, M.D. | | Deposit date: | 1997-07-08 | | Release date: | 1997-09-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy.
Nat.Struct.Biol., 3, 1996
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4QIP
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4A81
 | | Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in ternary complex with 8-Anilinonaphthalene-1-sulfonate (ANS) and deoxycholic acid | | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, 8-ANILINO-1-NAPHTHALENE SULFONATE, ... | | Authors: | Kofler, S, Brandstetter, H. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
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4A8G
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1QMR
 | | BIRCH POLLEN ALLERGEN BET V 1 MUTANT N28T, K32Q, E45S, P108G | | Descriptor: | MAJOR POLLEN ALLERGEN BET V 1-A | | Authors: | Henriksen, A, Holm, J.O, Spangfort, M.D, Gajhede, M. | | Deposit date: | 1999-10-06 | | Release date: | 2000-10-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Allergy vaccine engineering: epitope modulation of recombinant Bet v 1 reduces IgE binding but retains protein folding pattern for induction of protective blocking-antibody responses.
J Immunol., 173, 2004
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4Z3L
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1FSK
 | | COMPLEX FORMATION BETWEEN A FAB FRAGMENT OF A MONOCLONAL IGG ANTIBODY AND THE MAJOR ALLERGEN FROM BIRCH POLLEN BET V 1 | | Descriptor: | ANTIBODY HEAVY CHAIN FAB, IMMUNOGLOBULIN KAPPA LIGHT CHAIN, MAJOR POLLEN ALLERGEN BET V 1-A | | Authors: | Mirza, O, Henriksen, A, Ipsen, H, Larsen, J, Wissenbach, M, Spangfort, M, Gajhede, M. | | Deposit date: | 2000-09-11 | | Release date: | 2000-10-02 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1.
J.Immunol., 165, 2000
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7N0U
 | | Complex of recombinant Bet v 1 with Fab fragment of REGN5713 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, REGN5713 Fab fragment heavy chain, REGN5713 Fab fragment light chain, ... | | Authors: | Franklin, M.C, Romero Hernandez, A. | | Deposit date: | 2021-05-26 | | Release date: | 2021-08-11 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response.
J.Allergy Clin.Immunol., 149, 2022
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1LLT
 | | BIRCH POLLEN ALLERGEN BET V 1 MUTANT E45S | | Descriptor: | POLLEN ALLERGEN BET V 1 | | Authors: | Spangfort, M.D, Mirza, O, Ipsen, H, Van Neerven, R.J, Gajhede, M, Larsen, J.N. | | Deposit date: | 2002-04-30 | | Release date: | 2003-10-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis.
J.Immunol., 171, 2003
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7MXL
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7N0V
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