7N0U

Complex of recombinant Bet v 1 with Fab fragment of REGN5713

Summary for 7N0U

Entry DOI	10.2210/pdb7n0u/pdb
Descriptor	REGN5713 Fab fragment heavy chain, REGN5713 Fab fragment light chain, Recombinant Bet v 1, ... (6 entities in total)
Functional Keywords	birch pollen, allergy, neutralizing antibody, immunotherapy, allergen
Biological source	Mus musculus More
Total number of polymer chains	3
Total formula weight	68154.82
Authors	Franklin, M.C.,Romero Hernandez, A. (deposition date: 2021-05-26, release date: 2021-08-11, Last modification date: 2023-10-18)
Primary citation	Atanasio, A.,Franklin, M.C.,Kamat, V.,Hernandez, A.R.,Badithe, A.,Ben, L.H.,Jones, J.,Bautista, J.,Yancopoulos, G.D.,Olson, W.,Murphy, A.J.,Sleeman, M.A.,Orengo, J.M. Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response. J.Allergy Clin.Immunol., 149:200-211, 2022 Cited by PubMed: 34126155 DOI: 10.1016/j.jaci.2021.05.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation