7N0U

Complex of recombinant Bet v 1 with Fab fragment of REGN5713

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	REGN5713 Fab fragment heavy chain	polymer	221	23560.2	1		Mus musculus
2	L	REGN5713 Fab fragment light chain	polymer	214	23534.2	1		Mus musculus
3	C	Recombinant Bet v 1	polymer	187	20743.1	1	UniProt (P15494) Pfam (PF00407) In PDB	Betula pendula
4	L	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
6		water	water		18.0	11	Chemie (HOH)

Sequence modifications

C: 1 - 159 (UniProt: P15494)

PDB	External Database	Details
Leu 62	Phe 63	engineered mutation
Glu 160	-	expression tag
Gln 161	-	expression tag
Lys 162	-	expression tag
Leu 163	-	expression tag
Ile 164	-	expression tag
Ser 165	-	expression tag
Glu 166	-	expression tag
Glu 167	-	expression tag
Asp 168	-	expression tag
Leu 169	-	expression tag
Gly 170	-	expression tag
Gly 171	-	expression tag
Glu 172	-	expression tag
Gln 173	-	expression tag
Lys 174	-	expression tag
Leu 175	-	expression tag
Ile 176	-	expression tag
Ser 177	-	expression tag
Glu 178	-	expression tag
Glu 179	-	expression tag
Asp 180	-	expression tag
Leu 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	67837.6
Non-Polymers*	Number of molecules	2
	Total formula weight	317.3
All*	Total formula weight	68154.8

*Water molecules are not included.