4MNS

Crystal structure of the major pollen allergen Bet v 1-A in complex with P303

Summary for 4MNS

Entry DOI	10.2210/pdb4mns/pdb
Descriptor	Major pollen allergen Bet v 1-A, (3R,4R,5aR,11aR)-3-methyl-6,11-dioxo-2,3,4,5,5a,6,11,11a-octahydrothiepino[3,2-g]isoquinoline-4-carboxylic acid (3 entities in total)
Functional Keywords	major pollen allergen, allergen
Biological source	Betula pendula (white birch)
Cellular location	Cytoplasm: P15494
Total number of polymer chains	1
Total formula weight	17766.94
Authors	Leone, P.,Roussel, A. (deposition date: 2013-09-11, release date: 2015-03-11, Last modification date: 2023-09-20)
Primary citation	Nony, E.,Bouley, J.,Le Mignon, M.,Lemoine, P.,Jain, K.,Horiot, S.,Mascarell, L.,Pallardy, M.,Vincentelli, R.,Leone, P.,Roussel, A.,Batard, T.,Abiteboul, K.,Robin, B.,de Beaumont, O.,Arvidsson, M.,Rak, S.,Moingeon, P. Development and evaluation of a sublingual tablet based on recombinant Bet v 1 in birch pollen-allergic patients. Allergy, 70:795-804, 2015 Cited by PubMed: 25846209 DOI: 10.1111/all.12622 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation