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PDB: 32 results

1VIK
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HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 ORTHORHOMBIC FORM
Descriptor: HIV-1 PROTEASE, N-(1-BENZYL-2,3-DIHYDROXY-4-{3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRYLAMINO}-5-PHENYL-PENTYL)-3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRAMIDE
Authors:Lange-Savage, G, Berchtold, H, Liesum, A, Hilgenfeld, R.
Deposit date:1997-05-07
Release date:1998-12-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of HOE/BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms--structure/function relationship and influence of crystal packing.
Eur.J.Biochem., 248, 1997
1Q94
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Structures of HLA-A*1101 in complex with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle anchor residue
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ...
Authors:Li, L, McNicholl, J.M, Bouvier, M.
Deposit date:2003-08-22
Release date:2004-06-01
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
J.Immunol., 172, 2004
4EJL
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Apo HIV Protease (PR) dimer in closed form with fragment 1F1-N in the outside/top of flap
Descriptor: DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Tiefenbrunn, T, Stout, C.D.
Deposit date:2012-04-06
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.445 Å)
Cite:Small molecule regulation of protein conformation by binding in the Flap of HIV protease.
Acs Chem.Biol., 8, 2013
4DQG
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Crystal Structure of apo(G16C/L38C) HIV-1 Protease
Descriptor: ACETATE ION, Aspartyl protease, GLYCEROL, ...
Authors:Schiffer, C.A, Mittal, S.
Deposit date:2012-02-15
Release date:2012-03-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease.
J.Am.Chem.Soc., 134, 2012
1E28
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Nonstandard peptide binding of HLA-B*5101 complexed with HIV immunodominant epitope KM2(TAFTIPSI)
Descriptor: BETA-2 MICROGLOBULIN LIGHT CHAIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HEAVY CHAIN, PEPTIDE
Authors:Maenaka, K, Maenaka, T, Tomiyama, H, Takiguchi, M, Stuart, D.I, Jones, E.Y.
Deposit date:2000-05-18
Release date:2000-09-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes.
J Immunol., 165, 2000
3W39
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Crystal structure of HLA-B*5201 in complexed with HIV immunodominant epitope (TAFTIPSI)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-52 alpha chain, ...
Authors:Yagita, Y, Kuse, N, Kuroki, K, Gatanaga, H, Carlson, J.M, Chikata, T, Brumme, Z.L, Murakoshi, H, Akahoshi, T, Pfeifer, N, Mallal, S, John, M, Ose, T, Matsubara, H, Kanda, R, Fukunaga, Y, Honda, K, Kawashima, Y, Ariumi, Y, Oka, S, Maenaka, K, Takiguchi, M.
Deposit date:2012-12-13
Release date:2013-02-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity
J.Virol., 87, 2013
1P7Q
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Crystal Structure of HLA-A2 Bound to LIR-1, a Host and Viral MHC Receptor
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Willcox, B.E, Thomas, L.M, Bjorkman, P.J.
Deposit date:2003-05-05
Release date:2003-10-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor.
Nat.Immunol., 4, 2003
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