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PDB: 48 results

7SG5
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BU of 7sg5 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var2
Descriptor: CIS43_Var2 Fab Heavy chain, CIS43_Var2 Fab Light chain, GLYCEROL, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2021-10-05
Release date:2022-06-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
8FDD
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BU of 8fdd by Molmil
Crystal structure of Ky15.3 Fab in complex with circumsporozoite protein NPDP peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.3 Antibody, ...
Authors:Burn Aschner, C, Julien, J.P.
Deposit date:2022-12-02
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7SG6
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BU of 7sg6 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var10
Descriptor: CIS43_Var10 Fab Heavy chain, CIS43_Var10 Fab Light chain, GLYCEROL, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2021-10-05
Release date:2022-06-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
6PBV
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BU of 6pbv by Molmil
Crystal structure of Fab668 complex
Descriptor: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2019-06-14
Release date:2020-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.566 Å)
Cite:Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
3VDJ
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BU of 3vdj by Molmil
Crystal structure of circumsporozoite protein aTSR domain, R32 native form
Descriptor: Circumsporozoite (CS) protein
Authors:Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
8F9U
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BU of 8f9u by Molmil
Crystal structure of Ky15.7 Fab in complex with circumsporozoite protein NPDP peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.7 Antibody, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-24
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
8FB7
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BU of 8fb7 by Molmil
Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein NPDP peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.10 Antibody, ...
Authors:Prieto, K, Thai, E, Julien, J.P.
Deposit date:2022-11-29
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7RXP
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BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
6BQB
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BU of 6bqb by Molmil
MGG4 Fab in complex with peptide
Descriptor: GLYCEROL, MGG4 Fab heavy chain, MGG4 Fab light chain, ...
Authors:Oyen, D, Tan, J, Lanzavecchia, A, Wilson, I.A.
Deposit date:2017-11-27
Release date:2018-03-07
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.
Nat. Med., 24, 2018
8FA8
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BU of 8fa8 by Molmil
Crystal structure of Ky15.11 Fab in complex with circumsporozoite protein NDN peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NDN peptide, Ky15.11 Antibody, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-25
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7UFO
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BU of 7ufo by Molmil
Structure of PfCSP peptide 21 with antibody P3-42
Descriptor: GLYCEROL, P3-42 Fab Heavy chain, P3-42 Fab Light chain, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-03-23
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of PfCSP peptide 21 with antibody P3-42
To Be Published
7LKB
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BU of 7lkb by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.127
Descriptor: Circumsporozoite protein, SULFATE ION, m42.127 Fab heavy Chain, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-02-02
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
7RXL
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BU of 7rxl by Molmil
Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab1488 heavy chain, Fab1488 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.823 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
3VDK
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BU of 3vdk by Molmil
Crystal structure of circumsporozoite protein aTSR domain, R32 platinum-bound form
Descriptor: Circumsporozoite (CS) protein, PLATINUM (II) ION
Authors:Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
8F9T
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BU of 8f9t by Molmil
Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein NPDP peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.2 Antibody, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-24
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7RQQ
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BU of 7rqq by Molmil
Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP
Descriptor: 1,2-ETHANEDIOL, F10 Heavy Chain, L9 Kappa Chain, ...
Authors:Hurlburt, N.K, Pancera, M.
Deposit date:2021-08-06
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
8FBA
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BU of 8fba by Molmil
Crystal structure of Ky315 Fab in complex with circumsporozoite protein DND peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein DND peptide, Ky315 Antibody, ...
Authors:Burn Aschner, C, Julien, J.P.
Deposit date:2022-11-29
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7LKG
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BU of 7lkg by Molmil
Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.151
Descriptor: Circumsporozoite protein, m43.151 Fab Heavy Chain, m43.151 Fab Light chain
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-02-02
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
3VDL
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BU of 3vdl by Molmil
Crystal structure of circumsporozoite protein aTSR domain, P43212 form
Descriptor: Circumsporozoite (CS) protein
Authors:Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
6PBW
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BU of 6pbw by Molmil
Crystal structure of Fab667 complex
Descriptor: Fab667 heavy chain, Fab667 light chain, GLYCEROL, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2019-06-14
Release date:2020-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.058 Å)
Cite:Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
8F9S
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BU of 8f9s by Molmil
Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein NDN peptide
Descriptor: 1,2-ETHANEDIOL, Circumsporozoite protein NDN peptide, Ky15.2 Antibody, ...
Authors:Thai, E, Julien, J.P.
Deposit date:2022-11-24
Release date:2023-11-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
7RXI
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BU of 7rxi by Molmil
Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
Descriptor: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
Authors:Pholcharee, T, Oyen, D, Wilson, I.A.
Deposit date:2021-08-23
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7UYM
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BU of 7uym by Molmil
850 Fab in complex with NANPNANPNANP peptide
Descriptor: 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein, ...
Authors:Kucharska, I, Prieto, K, Julien, J.P.
Deposit date:2022-05-06
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
7UFN
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BU of 7ufn by Molmil
Structure of PfCSP peptide 21 with antibody P3-21
Descriptor: P3-21 Fab Heavy chain, P3-21 Fab Light chain, PfCSP peptide 21, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2022-03-22
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of PfCSP peptide 21 with antibody P3-21
To Be Published
7RQR
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BU of 7rqr by Molmil
Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP
Descriptor: 1,2-ETHANEDIOL, F10 Kappa Chain, L9 Heavy Chain, ...
Authors:Hurlburt, N.K, Pancera, M.
Deposit date:2021-08-06
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022

 

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