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PDB: 2 results

2HJH
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BU of 2hjh by Molmil
Crystal Structure of the Sir2 deacetylase
Descriptor: (2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL ACETATE, NAD-dependent histone deacetylase SIR2, NICOTINAMIDE, ...
Authors:Hall, B.E, Ellenberger, T.E.
Deposit date:2006-06-30
Release date:2008-04-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Autoregulation of the yeast Sir2 deacetylase by reaction and trapping of a pseudosubstrate motif in the active site
To be Published
4IAO
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BU of 4iao by Molmil
Crystal structure of Sir2 C543S mutant in complex with SID domain of Sir4
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent histone deacetylase SIR2, Regulatory protein SIR4, ...
Authors:Hsu, H.C, Wang, C.L, Wang, M, Yang, N, Chen, Z, Sternglanz, R, Xu, R.M.
Deposit date:2012-12-07
Release date:2012-12-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding
Genes Dev., 27, 2013

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