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PDB: 58 results

5FAF
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N184K pathological variant of gelsolin domain 2 (orthorhombic form)
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Boni, F, Milani, M, Ricagno, s, Bolognesi, M, de Rosa, M.
Deposit date:2015-12-11
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
6QW3
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BU of 6qw3 by Molmil
Calcium-bound gelsolin domain 2
Descriptor: CALCIUM ION, Gelsolin
Authors:Scalone, E, Boni, F, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2019-03-05
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion.
Biochem.Biophys.Res.Commun., 518, 2019
6LJE
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Crystal structure of gelsolin G3 domain (calcium and magnesium condition)
Descriptor: CALCIUM ION, GLYCEROL, Gelsolin
Authors:Takeda, S.
Deposit date:2019-12-14
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel inter-domain Ca2+-binding site in the gelsolin superfamily protein fragmin.
J.Muscle Res.Cell.Motil., 41, 2020
6LJF
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Crystal structure of gelsolin G3 domain (calcium condition)
Descriptor: CALCIUM ION, GLYCEROL, Gelsolin
Authors:Takeda, S.
Deposit date:2019-12-14
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Novel inter-domain Ca2+-binding site in the gelsolin superfamily protein fragmin.
J.Muscle Res.Cell.Motil., 41, 2020
2FH1
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BU of 2fh1 by Molmil
C-terminal half of gelsolin soaked in low calcium at pH 4.5
Descriptor: CALCIUM ION, Gelsolin
Authors:Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C.
Deposit date:2005-12-23
Release date:2006-06-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Calcium ion exchange in crystalline gelsolin
J.Mol.Biol., 357, 2006
3CIP
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BU of 3cip by Molmil
Complex of Dictyostelium Discoideum Actin with Gelsolin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, GLYCEROL, ...
Authors:Baek, K, Dominguez, R.
Deposit date:2008-03-11
Release date:2008-08-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1KCQ
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Human Gelsolin Domain 2 with a Cd2+ bound
Descriptor: CADMIUM ION, GELSOLIN
Authors:Kazmirski, S.L, Isaacson, R.L, An, C, Buckle, A, Johnson, C.M, Daggett, V, Fersht, A.R.
Deposit date:2001-11-09
Release date:2002-01-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type.
Nat.Struct.Biol., 9, 2002
3CI5
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BU of 3ci5 by Molmil
Complex of Phosphorylated Dictyostelium Discoideum Actin with Gelsolin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, GLYCEROL, ...
Authors:Baek, K, Dominguez, R.
Deposit date:2008-03-10
Release date:2008-08-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
5O2Z
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BU of 5o2z by Molmil
Domain swap dimer of the G167R variant of gelsolin second domain
Descriptor: ACETATE ION, CALCIUM ION, CITRATE ANION, ...
Authors:Boni, F, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2017-05-23
Release date:2017-11-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein.
Hum. Mol. Genet., 27, 2018
5FAE
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N184K pathological variant of gelsolin domain 2 (trigonal form)
Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Boni, F, Milani, M, Ricagno, S, Bolognesi, M, de Rosa, M.
Deposit date:2015-12-11
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
1D4X
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Crystal Structure of Caenorhabditis Elegans Mg-ATP Actin Complexed with Human Gelsolin Segment 1 at 1.75 A resolution.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, C. ELEGANS ACTIN 1/3, CALCIUM ION, ...
Authors:Vorobiev, S, Ono, S, Almo, S.C.
Deposit date:1999-10-06
Release date:2001-05-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of nonvertebrate actin: implications for the ATP hydrolytic mechanism.
Proc.Natl.Acad.Sci.Usa, 100, 2003
4PKG
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BU of 4pkg by Molmil
Complex of ATP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rao, J.N, Dominguez, R.
Deposit date:2014-05-14
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
Science, 345, 2014
1NLV
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BU of 1nlv by Molmil
Crystal Structure Of Dictyostelium Discoideum Actin Complexed With Ca ATP And Human Gelsolin Segment 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ...
Authors:Vorobiev, S.M, Welti, S, Condeelis, J, Almo, S.C.
Deposit date:2003-01-07
Release date:2003-01-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of Non-Vertebrate Actin: Implications For The ATP Hydrolytic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
1NM1
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BU of 1nm1 by Molmil
Crystal Structure of D. Dicsoideum Actin Complexed With Gelsolin Segment 1 and Mg ATP at 1.8 A Resolution
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ...
Authors:Vorobiev, S.M, Welti, S, Condeelis, J, Almo, S.C.
Deposit date:2003-01-08
Release date:2003-01-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of Non-Vertebrate Actin: Implications For The ATP Hydrolytic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
6H1F
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BU of 6h1f by Molmil
Structure of the nanobody-stabilized gelsolin D187N variant (second domain)
Descriptor: Gelsolin, THIOCYANATE ION, gelsolin nanobody, ...
Authors:Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2018-07-11
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
1NMD
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BU of 1nmd by Molmil
Crystal Structure of D. Discoideum Actin-Gelsolin Segment 1 Complex Crystallized In Presence Of Lithium ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ...
Authors:Vorobiev, S.M, Welti, S, Condeelis, J, Almo, S.C.
Deposit date:2003-01-09
Release date:2003-02-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure Of The Non-Vertebrate Actin: Implications For The ATP Hydrolytic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
1YAG
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BU of 1yag by Molmil
STRUCTURE OF THE YEAST ACTIN-HUMAN GELSOLIN SEGMENT 1 COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Vorobiev, S, Strokopytov, B, Frieden, C, Almo, S.C.
Deposit date:1998-10-09
Release date:1999-10-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of nonvertebrate actin: Implications for the ATP hydrolytic mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
1T44
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BU of 1t44 by Molmil
Structural basis of actin sequestration by thymosin-B4: Implications for arp2/3 activation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha, ...
Authors:Irobi, E, Aguda, A.H, Larsson, M, Burtnick, L.D, Robinson, R.C.
Deposit date:2004-04-28
Release date:2004-09-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins.
Embo J., 23, 2004
1P8X
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BU of 1p8x by Molmil
The Calcium-Activated C-terminal half of gelsolin
Descriptor: CALCIUM ION, Gelsolin precursor, plasma
Authors:Narayan, K, Burtnick, L.D, Robinson, R.C.
Deposit date:2003-05-08
Release date:2003-10-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Activation in isolation: Exposure of the actin-binding site in the C-terminal half of gelsolin does not require actin
FEBS LETT., 552, 2003
1C0G
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BU of 1c0g by Molmil
CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 228: Q228K/T229A/A230Y/E360H)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, PROTEIN (CHIMERIC ACTIN), ...
Authors:Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T.
Deposit date:1999-07-16
Release date:2000-03-01
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras.
J.Mol.Biol., 296, 2000
2FF3
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BU of 2ff3 by Molmil
Crystal structure of Gelsolin domain 1:N-wasp V2 motif hybrid in complex with actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Xue, B, Aguda, A.H, Robinson, R.C.
Deposit date:2005-12-19
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins
Structure, 14, 2006
1ESV
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BU of 1esv by Molmil
COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ALPHA ACTIN, CALCIUM ION, ...
Authors:Morton, W.M, Ayscough, K.A, McLaughlin, P.J.
Deposit date:2000-04-11
Release date:2000-07-19
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Latrunculin alters the actin-monomer subunit interface to prevent polymerization.
Nat.Cell Biol., 2, 2000
2FF6
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BU of 2ff6 by Molmil
Crystal structure of Gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Aguda, A.H, Xue, B, Robinson, R.C.
Deposit date:2005-12-19
Release date:2006-03-21
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins
Structure, 14, 2006
1YVN
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THE YEAST ACTIN VAL 159 ASN MUTANT COMPLEX WITH HUMAN GELSOLIN SEGMENT 1.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Vorobiev, S.M, Belmont, L.D, Drubin, D.G, Almo, S.C.
Deposit date:1999-03-23
Release date:2000-03-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of yeast actin V159N mutant
To be Published
4PKH
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BU of 4pkh by Molmil
Complex of ADP-actin With the N-terminal Actin-Binding Domain of Tropomodulin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rao, J.N, Dominguez, R.
Deposit date:2014-05-14
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Actin cytoskeleton. Mechanism of actin filament pointed-end capping by tropomodulin.
Science, 345, 2014

 

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