8BKZ
 
 | | GroEL:GroES-ATP complex under continuous turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-09 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8P4M
 | | CryoEM structure of a C7-symmetrical GroEL7-GroES7 cage in presence of ADP-BeFx | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | Authors: | Wagner, J, Beck, F, Bracher, A, Caravajal, A.I, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | Deposit date: | 2023-05-23 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Visualizing chaperonin function in situ by cryo-electron tomography.
Nature, 633, 2024
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8BMT
 | | Structure of GroEL:GroES-ATP complex plunge frozen 200 ms after reaction initiation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Efremov, R, Torino, S. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BM1
 | | Structure of GroEL:GroES-ATP complex under continuous turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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1PCQ
 | | Crystal structure of groEL-groES | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | Authors: | Chaudhry, C, Farr, G.W, Todd, M.J, Rye, H.S, Brunger, A.T, Adams, P.D, Horwich, A.L, Sigler, P.B. | | Deposit date: | 2003-05-16 | | Release date: | 2003-10-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.808 Å) | | Cite: | Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics.
Embo J., 22, 2003
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1SVT
 | | Crystal structure of GroEL14-GroES7-(ADP-AlFx)7 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | Authors: | Chaudhry, C, Horwich, A.L, Brunger, A.T, Adams, P.D. | | Deposit date: | 2004-03-29 | | Release date: | 2005-03-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.808 Å) | | Cite: | Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states.
J.Mol.Biol., 342, 2004
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8P4N
 | | CryoEM structure of a GroEL7-GroES7 cage with encapsulated disordered substrate MetK in the presence of ADP-BeFx | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | Authors: | Wagner, J, Beck, F, Bracher, A, Caravajal, A.I, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | Deposit date: | 2023-05-23 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Visualizing chaperonin function in situ by cryo-electron tomography.
Nature, 633, 2024
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8QXT
 | | CryoEM structure of a GroEL14-GroES7 complex in presence of ADP-BeFx with narrow GroEL7 trans ring conformation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | Authors: | Wagner, J, Caravajal, A.I, Beck, F, Bracher, A, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | Deposit date: | 2023-10-25 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Visualizing chaperonin function in situ by cryo-electron tomography.
Nature, 633, 2024
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1PF9
 | | GroEL-GroES-ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, groEL protein, ... | | Authors: | Chaudhry, C, Farr, G.W, Todd, M.J, Rye, H.S, Brunger, A.T, Adams, P.D, Horwich, A.L, Sigler, P.B. | | Deposit date: | 2003-05-24 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.993 Å) | | Cite: | Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics.
Embo J., 22, 2003
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1SX4
 | | GroEL-GroES-ADP7 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, groEL protein, ... | | Authors: | Chaudhry, C, Horwich, A.L, Brunger, A.T, Adams, P.D. | | Deposit date: | 2004-03-30 | | Release date: | 2005-03-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states.
J.Mol.Biol., 342, 2004
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1AON
 | | CRYSTAL STRUCTURE OF THE ASYMMETRIC CHAPERONIN COMPLEX GROEL/GROES/(ADP)7 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GROEL, GROEL/GROES COMPLEX, ... | | Authors: | Xu, Z, Horwich, A.L, Sigler, P.B. | | Deposit date: | 1997-07-08 | | Release date: | 1997-10-15 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex.
Nature, 388, 1997
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8P4O
 | | CryoEM structure of a GroEL7-GroES7 cage with encapsulated ordered substrate MetK in the presence of ADP-BeFx | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | Authors: | Wagner, J, Beck, F, Bracher, A, Caravajal, A.I, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | Deposit date: | 2023-05-23 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Visualizing chaperonin function in situ by cryo-electron tomography.
Nature, 633, 2024
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8QXS
 | | CryoEM structure of a GroEL14-GroES7 complex in presence of ADP-BeFx with wide GroEL7 trans ring conformation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | | Authors: | Wagner, J, Caravajal, A.I, Beck, F, Bracher, A, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | | Deposit date: | 2023-10-25 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Visualizing chaperonin function in situ by cryo-electron tomography.
Nature, 633, 2024
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7PBJ
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8BMO
 | | Structure of GroEL:GroES complex exhibiting ADP-conformation in trans ring obtained under the continuous turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BM0
 | | Structure of GroEL:GroES-ATP complex plunge frozen 200 ms after reaction initiation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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7PBX
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5OPX
 | | Crystal structure of the GroEL mutant A109C in complex with GroES and ADP BeF2 | | Descriptor: | 10 kDa chaperonin, 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Yan, X, Shi, Q, Bracher, A, Milicic, G, Singh, A.K, Hartl, F.U, Hayer-Hartl, M. | | Deposit date: | 2017-08-10 | | Release date: | 2018-01-10 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.64 Å) | | Cite: | GroEL Ring Separation and Exchange in the Chaperonin Reaction.
Cell, 172, 2018
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8BA9
 | | CryoEM structure of GroEL-GroES-ADP.AlF3-Rubisco. | | Descriptor: | 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | | Authors: | Gardner, S, Saibil, H.R. | | Deposit date: | 2022-10-11 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc Natl Acad Sci U S A, 120, 2023
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3WVL
 | | Crystal structure of the football-shaped GroEL-GroES complex (GroEL: GroES2:ATP14) from Escherichia coli | | Descriptor: | 10 kDa chaperonin, 60 kDa chaperonin, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Koike-Takeshita, A, Arakawa, T, Taguchi, H, Shimamura, T. | | Deposit date: | 2014-05-23 | | Release date: | 2014-09-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.788 Å) | | Cite: | Crystal structure of a symmetric football-shaped GroEL:GroES2-ATP14 complex determined at 3.8 angstrom reveals rearrangement between two GroEL rings.
J.Mol.Biol., 426, 2014
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7VWX
 | | CryoEM structure of football-shaped GroEL:ES2 with RuBisCO | | Descriptor: | Chaperonin GroEL, Co-chaperonin GroES, Ribulose bisphosphate carboxylase | | Authors: | Kim, H, Roh, S.H. | | Deposit date: | 2021-11-12 | | Release date: | 2022-01-12 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Cryo-EM structures of GroEL:ES 2 with RuBisCO visualize molecular contacts of encapsulated substrates in a double-cage chaperonin.
Iscience, 25, 2022
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2C7C
 | | FITTED COORDINATES FOR GROEL-ATP7-GROES CRYO-EM COMPLEX (EMD-1180) | | Descriptor: | 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ... | | Authors: | Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R. | | Deposit date: | 2005-11-22 | | Release date: | 2006-01-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
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2C7D
 | | Fitted coordinates for GroEL-ADP7-GroES Cryo-EM complex (EMD-1181) | | Descriptor: | 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ... | | Authors: | Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R. | | Deposit date: | 2005-11-22 | | Release date: | 2006-01-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.7 Å) | | Cite: | Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
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3ZPZ
 | | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | | Descriptor: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | | Deposit date: | 2013-03-04 | | Release date: | 2013-06-19 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein
Cell(Cambridge,Mass.), 153, 2013
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3ZQ0
 | | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | | Descriptor: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | | Deposit date: | 2013-03-04 | | Release date: | 2013-06-19 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (9.2 Å) | | Cite: | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein
Cell(Cambridge,Mass.), 153, 2013
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