5KDO
 
 | | Heterotrimeric complex of the 4 alanine insertion variant of the Gi alpha1 subunit and the Gbeta1-Ggamma1 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | | Authors: | Kaya, A.I, Lokits, A.D, Gilbert, J, Iverson, T.M, Meiler, J, Hamm, H.E. | | Deposit date: | 2016-06-08 | | Release date: | 2016-08-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor.
J.Biol.Chem., 291, 2016
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1GOT
 | | HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS | | Descriptor: | GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ... | | Authors: | Lambright, D.G, Sondek, J, Bohm, A, Skiba, N.P, Hamm, H.E, Sigler, P.B. | | Deposit date: | 1996-08-07 | | Release date: | 1997-03-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The 2.0 A crystal structure of a heterotrimeric G protein.
Nature, 379, 1996
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1TBG
 | | BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN | | Descriptor: | TRANSDUCIN | | Authors: | Sondek, J.S, Bohm, A, Lambright, D.G, Hamm, H.E, Sigler, P.B. | | Deposit date: | 1996-06-15 | | Release date: | 1997-04-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Nature, 379, 1996
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6B20
 | | Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody regulator | | Descriptor: | CHLORIDE ION, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | | Authors: | Gulati, S, Kiser, P.D, Palczewski, K. | | Deposit date: | 2017-09-19 | | Release date: | 2018-05-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.
Nat Commun, 9, 2018
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2TRC
 | | PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX | | Descriptor: | GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN | | Authors: | Gaudet, R, Bohm, A, Sigler, P.B. | | Deposit date: | 1997-01-06 | | Release date: | 1997-06-05 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
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1A0R
 | | HETEROTRIMERIC COMPLEX OF PHOSDUCIN/TRANSDUCIN BETA-GAMMA | | Descriptor: | FARNESYL, PHOSDUCIN, TRANSDUCIN (BETA SUBUNIT), ... | | Authors: | Loew, A, Ho, Y.-K, Blundell, T.L, Bax, B. | | Deposit date: | 1997-12-05 | | Release date: | 1998-12-30 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Phosducin induces a structural change in transducin beta gamma.
Structure, 6, 1998
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1B9Y
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1B9X
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7O7F
 | | Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist | | Descriptor: | C-C chemokine receptor type 5, C-C motif chemokine 5, Fab antibody fragment heavy chain, ... | | Authors: | Isaikina, P, Tsai, C.-J, Dietz, N.B, Pamula, F, Goldie, K.N, Schertler, G.F.X, Maier, T, Stahlberg, H, Deupi, X, Grzesiek, S. | | Deposit date: | 2021-04-13 | | Release date: | 2021-06-30 | | Last modified: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist.
Sci Adv, 7, 2021
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6OYA
 | | Structure of the Rhodopsin-Transducin-Nanobody Complex | | Descriptor: | Camelid antibody VHH fragment, Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | | Deposit date: | 2019-05-14 | | Release date: | 2019-07-24 | | Last modified: | 2019-12-04 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
Mol.Cell, 75, 2019
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6OY9
 | | Structure of the Rhodopsin-Transducin Complex | | Descriptor: | Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | | Authors: | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | | Deposit date: | 2019-05-14 | | Release date: | 2019-07-24 | | Last modified: | 2019-12-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.
Mol.Cell, 75, 2019
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6QNO
 | | Rhodopsin-Gi protein complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab antibody fragment heavy chain, Fab antibody fragment light chain, ... | | Authors: | Tsai, C.-J, Marino, J, Adaixo, R.J, Pamula, F, Muehle, J, Maeda, S, Flock, T, Taylor, N.M.I, Mohammed, I, Matile, H, Dawson, R.J.P, Deupi, X, Stahlberg, H, Schertler, G.F.X. | | Deposit date: | 2019-02-11 | | Release date: | 2019-07-10 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.38 Å) | | Cite: | Cryo-EM structure of the rhodopsin-G alpha i-beta gamma complex reveals binding of the rhodopsin C-terminal tail to the G beta subunit.
Elife, 8, 2019
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1MF6
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