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PDB: 6 results
1B12
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BU of 1b12 by Molmil
CRYSTAL STRUCTURE OF TYPE 1 SIGNAL PEPTIDASE FROM ESCHERICHIA COLI IN COMPLEX WITH A BETA-LACTAM INHIBITOR
Descriptor: PHOSPHATE ION, SIGNAL PEPTIDASE I, prop-2-en-1-yl (2S)-2-[(2S,3R)-3-(acetyloxy)-1-oxobutan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylate
Authors:Paetzel, M, Dalbey, R, Strynadka, N.C.J.
Deposit date:1999-11-24
Release date:1999-12-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor.
Nature, 396, 1998
3IIQ
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BU of 3iiq by Molmil
Crystallographic analysis of bacterial signal peptidase in ternary complex with Arylomycin A2 and a beta-sultam inhibitor
Descriptor: 10-METHYLUNDECANOIC ACID, 4-[(1,1-dioxido-1,2-thiazetidin-2-yl)carbonyl]morpholine, ACETONITRILE, ...
Authors:Paetzel, M.
Deposit date:2009-08-03
Release date:2009-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic Analysis of Bacterial Signal Peptidase in Ternary Complex with Arylomycin A2 and a Beta-Sultam Inhibitor.
Biochemistry, 48, 2009
1KN9
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CRYSTAL STRUCTURE OF A BACTERIAL SIGNAL PEPTIDASE APO-ENZYME, IMPLICATIONS FOR SIGNAL PEPTIDE BINDING AND THE SER-LYS DYAD MECHANISM.
Descriptor: Signal peptidase I
Authors:Paetzel, M, Dalbey, R.E, Strynadka, N.C.J.
Deposit date:2001-12-18
Release date:2002-01-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
J.Biol.Chem., 277, 2002
6B88
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BU of 6b88 by Molmil
E. coli LepB in complex with GNE0775 ((4S,7S,10S)-10-((S)-4-amino-2-(2-(4-(tert-butyl)phenyl)-4-methylpyrimidine-5-carboxamido)-N-methylbutanamido)-16,26-bis(2-aminoethoxy)-N-(2-iminoethyl)-7-methyl-6,9-dioxo-5,8-diaza-1,2(1,3)-dibenzenacyclodecaphane-4-carboxamide)
Descriptor: (8S,11S,14S)-14-{[(2S)-4-amino-2-{[2-(4-tert-butylphenyl)-4-methylpyrimidine-5-carbonyl]amino}butanoyl](methyl)amino}-3,18-bis(2-aminoethoxy)-N-[(2Z)-2-iminoethyl]-11-methyl-10,13-dioxo-9,12-diazatricyclo[13.3.1.1~2,6~]icosa-1(19),2(20),3,5,15,17-hexaene-8-carboxamide, PENTAETHYLENE GLYCOL, Signal peptidase I
Authors:Murray, J.M, Rouge, L.
Deposit date:2017-10-05
Release date:2018-10-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.407 Å)
Cite:Optimized arylomycins are a new class of Gram-negative antibiotics.
Nature, 561, 2018
3S04
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BU of 3s04 by Molmil
Crystal structure of Escherichia coli type I signal peptidase in complex with an Arylomycin Lipoglycopeptide Antibiotic
Descriptor: 14-methylhexadec-9-enoic acid, Glyco-Arylomycin, Signal peptidase I, ...
Authors:Paetzel, M, Luo, C.
Deposit date:2011-05-13
Release date:2011-10-05
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Synthesis and characterization of the arylomycin lipoglycopeptide antibiotics and the crystallographic analysis of their complex with signal peptidase.
J.Am.Chem.Soc., 133, 2011
1T7D
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BU of 1t7d by Molmil
Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Descriptor: 10-METHYLUNDECANOIC ACID, ARYLOMYCIN A2, SIGNAL PEPTIDASE I
Authors:Paetzel, M, Goodall, J.J, Kania, M, Dalbey, R.E, Page, M.G.P.
Deposit date:2004-05-09
Release date:2004-07-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystallographic and Biophysical Analysis of a Bacterial Signal Peptidase in Complex with a Lipopeptide Based Inhibitor.
J.Biol.Chem., 279, 2004

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