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PDB: 9 results

4RWF
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BU of 4rwf by Molmil
Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin
Descriptor: 1,2-ETHANEDIOL, Adrenomedullin, Maltose transporter subunit, ...
Authors:Booe, J, Pioszak, A.
Deposit date:2014-12-03
Release date:2015-05-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
6V2E
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BU of 6v2e by Molmil
Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant
Descriptor: ADM, AMINO GROUP, FORMIC ACID, ...
Authors:Booe, J.M, Pioszak, A.A.
Deposit date:2019-11-22
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors.
Acs Pharmacol Transl Sci, 3, 2020
3AQE
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BU of 3aqe by Molmil
Crystal structure of the extracellular domain of human RAMP2
Descriptor: Receptor activity-modifying protein 2
Authors:Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Shindo, T, Yokoyama, S.
Deposit date:2010-10-29
Release date:2011-11-09
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding
Protein Sci., 21, 2012
2XVT
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Structure of the extracellular domain of human RAMP2
Descriptor: CALCIUM ION, RECEPTOR ACTIVITY-MODIFYING PROTEIN 2
Authors:Quigley, A, Pike, A.C.W, Burgess-Brown, N, Krojer, T, Shrestha, L, Goubin, S, Kim, J, Das, S, Muniz, J.R.C, Canning, P, Chaikuad, A, Vollmar, M, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Barr, A.J, Carpenter, E.P.
Deposit date:2010-10-31
Release date:2010-12-29
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the Extracellular Domain of Human Ramp2
To be Published
7TYX
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Human Amylin2 Receptor in complex with Gs and rat amylin peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ...
Authors:Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M.
Deposit date:2022-02-14
Release date:2022-03-30
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:A structural basis for amylin receptor phenotype.
Science, 375, 2022
3AQF
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BU of 3aqf by Molmil
Crystal structure of the human CRLR/RAMP2 extracellular complex
Descriptor: Calcitonin gene-related peptide type 1 receptor, Receptor activity-modifying protein 2
Authors:Kusano, S, Kukimono-Niino, M, Shirouzu, M, Shindo, T, Yokoyama, S.
Deposit date:2010-10-29
Release date:2011-11-02
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding
Protein Sci., 21, 2012
6UUN
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BU of 6uun by Molmil
CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin peptide
Descriptor: ADM, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R.
Deposit date:2019-10-30
Release date:2020-03-25
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
Acs Pharmacol Transl Sci, 3, 2020
7TYY
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BU of 7tyy by Molmil
Human Amylin2 Receptor in complex with Gs and salmon calcitonin peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin receptor, ...
Authors:Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M.
Deposit date:2022-02-14
Release date:2022-03-23
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A structural basis for amylin receptor phenotype.
Science, 375, 2022
7TYH
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BU of 7tyh by Molmil
Human Amylin2 Receptor in complex with Gs and human calcitonin peptide
Descriptor: Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Cao, J, Belousoff, M.J, Johnson, R.M, Wootten, D.L, Sexton, P.M.
Deposit date:2022-02-13
Release date:2022-03-23
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A structural basis for amylin receptor phenotype.
Science, 375, 2022

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