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PDB: 18 results

4K8Y
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Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with Sunflower Trypsin Inhibitor (SFTI-1)
Descriptor: Kallikrein-4, Trypsin inhibitor 1
Authors:Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
Deposit date:2013-04-19
Release date:2014-04-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
4KEL
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Atomic resolution crystal structure of Kallikrein-Related Peptidase 4 complexed with a modified SFTI inhibitor FCQR(N)
Descriptor: Kallikrein-4, Trypsin inhibitor 1
Authors:Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
Deposit date:2013-04-25
Release date:2014-04-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.148 Å)
Cite:KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.
Biochemistry, 58, 2019
6O21
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Crystal Structure of Human KLK4 in Complex With Cleaved SFTI-FCQR(Asn14)[1,14] Inhibitor
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Kallikrein 4 (Prostase, enamel matrix, ...
Authors:Ilyichova, O.V, Buckle, A.M.
Deposit date:2019-02-22
Release date:2019-03-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.
Biochemistry, 58, 2019
4K1E
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Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with a modified SFTI inhibitor FCQR
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Kallikrein-4, LITHIUM ION, ...
Authors:Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
Deposit date:2013-04-04
Release date:2014-04-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
7JOD
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Crytsal structure of BbKI complexed with Human Kallikrein 4
Descriptor: CADMIUM ION, CHLORIDE ION, Kallikrein 4 (Prostase, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-06
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
7JQK
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Crystal structure of the R64A mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4
Descriptor: CADMIUM ION, CHLORIDE ION, Kallikrein-4, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-11
Release date:2021-07-21
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
7JQN
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Crystal structure of the R64M mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4
Descriptor: CADMIUM ION, CHLORIDE ION, Kallikrein-4, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-11
Release date:2021-07-21
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
7JQO
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Crystal structure of the R64D mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4
Descriptor: CADMIUM ION, CHLORIDE ION, Kallikrein-4, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-11
Release date:2021-07-21
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
6NVB
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Crystal structure of the inhibitor-free form of the serine protease kallikrein-4
Descriptor: GLYCEROL, Kallikrein-4, SULFATE ION
Authors:Riley, B.T, Buckle, A.M, McGowan, S.
Deposit date:2019-02-04
Release date:2019-07-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.636 Å)
Cite:Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.
Acta Crystallogr.,Sect.F, 75, 2019
7JOW
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BU of 7jow by Molmil
Crystal structure of BbKI complexed with Human Kallikrein 4
Descriptor: CADMIUM ION, CHLORIDE ION, Kallikrein 4 (Prostase, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-07
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
2BDG
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Human Kallikrein 4 complex with nickel and p-aminobenzamidine
Descriptor: CHLORIDE ION, Kallikrein-4, NICKEL (II) ION, ...
Authors:Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE)
Deposit date:2005-10-20
Release date:2006-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.
J.Mol.Biol., 362, 2006
6KBR
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BU of 6kbr by Molmil
Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex
Descriptor: GLYCEROL, K41043, Kallikrein-4
Authors:Kawaguchi, Y, Nishimiya, D.
Deposit date:2019-06-26
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.
Sci Rep, 9, 2019
7JOS
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BU of 7jos by Molmil
Crystal structure of BbKI complexed with Human Kallikrein 4
Descriptor: Kallikrein 4 (Prostase, enamel matrix, prostate), ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-07
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
7JQV
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BU of 7jqv by Molmil
Crystal structure of the R64F mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4
Descriptor: CHLORIDE ION, Kallikrein 4 (Prostase, enamel matrix, ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-11
Release date:2021-07-21
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.
Acta Crystallogr D Struct Biol, 77, 2021
4KGA
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BU of 4kga by Molmil
Crystal structure of kallikrein-related peptidase 4
Descriptor: 1,2-ETHANEDIOL, Kallikrein-4, NICKEL (II) ION
Authors:Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M.
Deposit date:2013-04-29
Release date:2014-04-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
Sci Rep, 6, 2016
7JOE
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BU of 7joe by Molmil
Crystal structure of BbKI complexed with Human Kallikrein 4
Descriptor: Kallikrein 4 (Prostase, enamel matrix, prostate), ...
Authors:Li, M, Wlodawer, A, Gustchina, A.
Deposit date:2020-08-06
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI
Acta Crystallogr.,Sect.D, 77, 2021
2BDI
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BU of 2bdi by Molmil
Human Kallikrein 4 complex with cobalt and p-aminobenzamidine
Descriptor: COBALT (II) ION, Kallikrein-4, P-AMINO BENZAMIDINE
Authors:Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE)
Deposit date:2005-10-20
Release date:2006-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.
J.Mol.Biol., 362, 2006
2BDH
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BU of 2bdh by Molmil
Human Kallikrein 4 complex with zinc and p-aminobenzamidine
Descriptor: Kallikrein-4, P-AMINO BENZAMIDINE, ZINC ION
Authors:Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE)
Deposit date:2005-10-20
Release date:2006-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.
J.Mol.Biol., 362, 2006

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