7JQV

Crystal structure of the R64F mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4

Summary for 7JQV

• Entry DOI: 10.2210/pdb7jqv/pdb
• Related: 7JOD 7JQK
• Descriptor: Kallikrein 4 (Prostase, enamel matrix, prostate), isoform CRA_a, Kunitz-type inihibitor, NONAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: human kallikrein 4, bauhinia bauhiniordes kallikrein inhibitor, structural protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 43370.88

Authors

Li, M.,Wlodawer, A.,Gustchina, A. (deposition date: 2020-08-11, release date: 2021-07-21, Last modification date: 2021-08-11)

• Primary citation: Li, M.,Srp, J.,Mares, M.,Wlodawer, A.,Gustchina, A.; Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.; Acta Crystallogr D Struct Biol, 77:1084-1098, 2021; PubMed: 34342281; DOI: 10.1107/S2059798321006483

Experimental method

X-RAY DIFFRACTION (2.1 Å)