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PDB: 8 results

5TXI
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BU of 5txi by Molmil
Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole
Descriptor: (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2016-11-16
Release date:2018-05-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 2018
5TW4
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BU of 5tw4 by Molmil
Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftaroline
Descriptor: CHLORIDE ION, Ceftaroline, bound form, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2016-11-11
Release date:2018-05-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 2018
5TY7
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BU of 5ty7 by Molmil
Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with nafcillin
Descriptor: (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4, SODIUM ION, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2016-11-18
Release date:2018-06-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 2018
5TX9
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BU of 5tx9 by Molmil
Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiprole
Descriptor: (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein 4, SODIUM ION, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2016-11-16
Release date:2018-05-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 2018
5TW8
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BU of 5tw8 by Molmil
Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftaroline
Descriptor: Ceftaroline, bound form, Penicillin-binding protein 4, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2016-11-11
Release date:2018-05-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 2018
5TY2
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BU of 5ty2 by Molmil
Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with nafcillin
Descriptor: (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, Penicillin-binding protein 4, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2016-11-18
Release date:2018-06-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 2018
6C39
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BU of 6c39 by Molmil
Apo crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4)
Descriptor: SODIUM ION, SULFATE ION, Serine-type D-Ala-D-Ala carboxypeptidase, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2018-01-09
Release date:2018-11-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 293, 2018
6C3K
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BU of 6c3k by Molmil
Apo crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R)
Descriptor: CHLORIDE ION, Penicillin-binding protein 4, SODIUM ION, ...
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2018-01-10
Release date:2018-11-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 293, 2018

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