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PDB: 10 results
7SL7
Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R)
Descriptor:
Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ...
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-10-22
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (3.1 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STJ
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1)
Descriptor:
Insulin, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-11-14
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (4.4 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL4
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation
Descriptor:
Insulin A chain, Insulin B chain, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-10-22
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (5 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL3
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation
Descriptor:
Insulin A chain, Insulin B chain, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-10-22
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (3.4 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL1
Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E)
Descriptor:
Insulin A chain, Insulin B chain, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-10-22
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (3.4 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL2
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation
Descriptor:
Insulin A chain, Insulin B chain, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-10-22
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (3.6 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STK
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2)
Descriptor:
Insulin, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-11-14
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (4 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL6
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation
Descriptor:
Insulin A chain, Insulin B chain, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-10-22
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (3.7 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STI
Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation
Descriptor:
Insulin, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-11-13
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (4.9 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STH
Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation
Descriptor:
Insulin, Insulin receptor
Authors:
Bai, X.C
,
Choi, E.
Deposit date:
2021-11-13
Release date:
2022-03-30
Last modified:
2022-04-27
Method:
ELECTRON MICROSCOPY (3.5 Å)
Cite:
Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
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PDB entries from 2024-04-24