7VDM
 
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with substance P | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Li, Y, Yang, F. | | Deposit date: | 2021-09-07 | | Release date: | 2021-12-01 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VDL
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7VDH
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state2 | | Descriptor: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Li, Y, Yang, F. | | Deposit date: | 2021-09-07 | | Release date: | 2021-12-01 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VV5
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state1 | | Descriptor: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Li, Y, Yang, F. | | Deposit date: | 2021-11-04 | | Release date: | 2021-12-01 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VV0
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7VV6
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80 (local) | | Descriptor: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Mas-related G-protein coupled receptor member X2 | | Authors: | Li, Y, Yang, F. | | Deposit date: | 2021-11-04 | | Release date: | 2021-12-01 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VUY
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7VV3
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7VUZ
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, state2 | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Li, Y, Yang, F. | | Deposit date: | 2021-11-04 | | Release date: | 2021-12-01 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
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7VV4
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9IV2
 | | Identification, structure and agonist design of an androgen membrane receptor. | | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, ... | | Authors: | Ping, Y.Q, Yang, Z. | | Deposit date: | 2024-07-22 | | Release date: | 2025-02-12 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 188, 2025
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9IV1
 | | Identification, structure and agonist design of an androgen membrane receptor. | | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Adhesion G-protein coupled receptor D1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Ping, Y.Q, Yang, Z. | | Deposit date: | 2024-07-22 | | Release date: | 2025-02-12 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 188, 2025
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8X9S
 | | Identification, structure and agonist design of an androgen membrane receptor. | | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, ... | | Authors: | Ping, Y.Q, Yang, Z. | | Deposit date: | 2023-12-01 | | Release date: | 2025-02-12 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 188, 2025
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8X9T
 | | Identification, structure and agonist design of an androgen membrane receptor | | Descriptor: | Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Ping, Y.Q, Yang, Z. | | Deposit date: | 2023-12-01 | | Release date: | 2025-02-12 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 188, 2025
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8X9U
 | | Identification, structure and agonist design of an androgen membrane receptor | | Descriptor: | (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, Adhesion G-protein coupled receptor D1, Gs protein alpha subunit, ... | | Authors: | Ping, Y.Q, Yang, Z. | | Deposit date: | 2023-12-01 | | Release date: | 2025-02-12 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Identification, structure, and agonist design of an androgen membrane receptor.
Cell, 188, 2025
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