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1KCO
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Structure of e131 Zeta Peptide, a Potent Antagonist of the High-Affinity IgE Receptor
Descriptor: e131 Zeta Peptide
Authors:Nakamura, G.R, Reynolds, M.E, Chen, Y.M, Starovasnik, M.A, Lowman, H.B.
Deposit date:2001-11-09
Release date:2002-03-06
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Proc.Natl.Acad.Sci.USA, 99, 2002
2BL0
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BU of 2bl0 by Molmil
Physarum polycephalum myosin II regulatory domain
Descriptor: CALCIUM ION, MAJOR PLASMODIAL MYOSIN HEAVY CHAIN, MYOSIN REGULATORY LIGHT CHAIN
Authors:Debreczeni, J.E, Farkas, L, Harmat, V, Nyitray, L.
Deposit date:2005-02-23
Release date:2005-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Evidence for Non-Canonical Binding of Ca2+ to a Canonical EF-Hand of a Conventional Myosin.
J.Biol.Chem., 280, 2005
1SYI
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BU of 1syi by Molmil
X-RAY STRUCTURE OF THE Y702F MUTANT OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 2.1 A RESOLUTION.
Descriptor: (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID, Glutamate receptor 2
Authors:Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S.
Deposit date:2004-04-01
Release date:2005-03-22
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.
Mol.Pharmacol., 67, 2005
4CCL
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BU of 4ccl by Molmil
X-Ray structure of E. coli ycfD
Descriptor: 50S RIBOSOMAL PROTEIN L16 ARGININE HYDROXYLASE, MANGANESE (II) ION, SULFATE ION
Authors:McDonough, M.A, Ho, C.H, Kershaw, N.J, Schofield, C.J.
Deposit date:2013-10-23
Release date:2014-04-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
2R8A
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BU of 2r8a by Molmil
Crystal structure of the long-chain fatty acid transporter FadL mutant delta N8
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Long-chain fatty acid transport protein
Authors:Hearn, E.M, Patel, D.R, Lepore, B.W, Indic, M, van den Berg, B.
Deposit date:2007-09-10
Release date:2008-09-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:From the Cover: Ligand-gated diffusion across the bacterial outer membrane.
Proc.Natl.Acad.Sci.USA, 108, 2011
8U25
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BU of 8u25 by Molmil
Crystal Structure of SARS-CoV-2 Main Protease (Mpro) L50F/E166A/L167F Triple Mutant
Descriptor: 3C-like proteinase
Authors:Kohaal, N, Lewandowski, E.M, Wang, J, Chen, Y.
Deposit date:2023-09-05
Release date:2024-11-06
Last modified:2025-02-12
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Distal protein-protein interactions contribute to nirmatrelvir resistance.
Nat Commun, 16, 2025
4KKI
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BU of 4kki by Molmil
Crystal Structure of Haptocorrin in Complex with CNCbl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANOCOBALAMIN, ...
Authors:Furger, E, Frei, D.C, Schibli, R, Fischer, E, Prota, A.E.
Deposit date:2013-05-06
Release date:2013-07-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for universal corrinoid recognition by the cobalamin transport protein haptocorrin.
J.Biol.Chem., 288, 2013
6I8T
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BU of 6i8t by Molmil
THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH AN ISOINDOLINONE INHIBITOR
Descriptor: (1~{R})-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1
Authors:Casale, E, Papeo, G, Montagnoli, A.
Deposit date:2018-11-21
Release date:2019-05-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.
Acs Med.Chem.Lett., 10, 2019
7RW9
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BU of 7rw9 by Molmil
AP2 bound to heparin in the bowl conformation
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Baker, R.W, Hollopeter, G, Partlow, E.A.
Deposit date:2021-08-19
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
8U4Y
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BU of 8u4y by Molmil
Crystal Structure of SARS-CoV-2 Main Protease (Mpro) L50F Mutant
Descriptor: 3C-like proteinase nsp5
Authors:Kohaal, N, Lewandowski, E.M, Wang, J, Chen, Y.
Deposit date:2023-09-11
Release date:2024-10-09
Last modified:2025-02-12
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Distal protein-protein interactions contribute to nirmatrelvir resistance.
Nat Commun, 16, 2025
7RW8
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BU of 7rw8 by Molmil
AP2 bound to heparin in the closed conformation
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Baker, R.W, Hollopeter, G, Partlow, E.A.
Deposit date:2021-08-19
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
6I8M
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BU of 6i8m by Molmil
THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH ISOINDOLINONE INHIBITOR
Descriptor: (1~{S})-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1
Authors:Casale, E, Papeo, G, Montagnoli, A.
Deposit date:2018-11-20
Release date:2019-05-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.
Acs Med.Chem.Lett., 10, 2019
2R89
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BU of 2r89 by Molmil
Crystal structure of the long-chain fatty acid transporter FadL mutant delta N3
Descriptor: Long-chain fatty acid transport protein
Authors:Hearn, E.M, Patel, D.R, Lepore, B.W, Indic, M, van den Berg, B.
Deposit date:2007-09-10
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:From the Cover: Ligand-gated diffusion across the bacterial outer membrane.
Proc.Natl.Acad.Sci.USA, 108, 2011
6I5M
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BU of 6i5m by Molmil
Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with GDP and formate ion
Descriptor: FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kravchenko, O, Nikonov, O, Gabdulkhakov, A, Stolboushkina, E, Arkhipova, V, Garber, M, Nikonov, S.
Deposit date:2018-11-13
Release date:2019-01-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The third structural switch in the archaeal translation initiation factor 2 (aIF2) molecule and its possible role in the initiation of GTP hydrolysis and the removal of aIF2 from the ribosome.
Acta Crystallogr D Struct Biol, 75, 2019
4KG2
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BU of 4kg2 by Molmil
Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Cefotaxime
Descriptor: Beta-lactamase, CEFOTAXIME, C3' cleaved, ...
Authors:Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J.
Deposit date:2013-04-28
Release date:2014-10-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Complexed structures of AmpC beta-lactamase
To be Published
4KG6
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BU of 4kg6 by Molmil
Crystal Structure of AmpC beta-lactamase N152G Mutant from E. coli
Descriptor: Beta-lactamase, PHOSPHATE ION
Authors:Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J.
Deposit date:2013-04-28
Release date:2014-10-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Complexed structures of AmpC beta-lactamase
To be Published
3D00
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BU of 3d00 by Molmil
Crystal structure of a tungsten formylmethanofuran dehydrogenase subunit e (fmde)-like protein (syn_00638) from syntrophus aciditrophicus at 1.90 A resolution
Descriptor: CHLORIDE ION, Tungsten formylmethanofuran dehydrogenase subunit E, ZINC ION
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-04-30
Release date:2008-05-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved alpha+beta core domain and an auxiliary C-terminal treble-clef zinc finger.
Acta Crystallogr.,Sect.F, 66, 2010
5A7U
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BU of 5a7u by Molmil
Single-particle cryo-EM of co-translational folded adr1 domain inside the E. coli ribosome exit tunnel.
Descriptor: REGULATORY PROTEIN ADR1, ZINC ION
Authors:Nilsson, O.B, Hedman, R, Marino, J, Wickles, S, Bischoff, L, Johansson, M, Muller-Lucks, A, Trovato, F, Puglisi, J.D, O'Brien, E, Beckmann, R, von Heijne, G.
Deposit date:2015-07-10
Release date:2015-09-16
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cotranslational Protein Folding Inside the Ribosome Exit Tunnel.
Cell Rep., 12, 2015
5K9T
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BU of 5k9t by Molmil
SecA-N68, a C-terminal truncation of the SecA ATPase from E. coli
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translocase subunit SecA
Authors:Shilton, B.H, Vezina, G.C.
Deposit date:2016-06-01
Release date:2017-06-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An alternate mode of oligomerization for E. coli SecA.
Sci Rep, 7, 2017
5AGW
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BU of 5agw by Molmil
Bcl-2 alpha beta-1 complex
Descriptor: APOPTOSIS REGULATOR BCL-2, BCL-2-LIKE PROTEIN 1, BCL-2-LIKE PROTEIN 11
Authors:Smith, B.J, F Lee, E, Checco, J.W, Gellman, S.H, Fairlie, W.D.
Deposit date:2015-02-04
Release date:2015-09-09
Last modified:2025-02-12
Method:X-RAY DIFFRACTION (2.695 Å)
Cite:Alpha Beta Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity on Living Cells
J.Am.Chem.Soc., 137, 2015
5A4K
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BU of 5a4k by Molmil
Crystal structure of the R139W variant of human NAD(P)H:quinone oxidoreductase
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1
Authors:Lienhart, W.D, Strandback, E, Gudipati, V, Uhl, M.K, Rantase, D.M, Zangger, K, Gruber, K, Macheroux, P.
Deposit date:2015-06-10
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1).
FEBS J., 284, 2017
7BNX
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BU of 7bnx by Molmil
Archeal holliday junction resolvase from Thermus thermophilus phage 15-6
Descriptor: Holliday junction resolvase, SULFATE ION
Authors:Hakansson, M, Ahlqvist, J, Linares Pasten, J.A, Jasilionis, A, Nordberg Karlsson, E, Al-Karadaghi, S.
Deposit date:2021-01-22
Release date:2022-02-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6.
Acta Crystallogr D Struct Biol, 78, 2022
1K7H
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BU of 1k7h by Molmil
CRYSTAL STRUCTURE OF SHRIMP ALKALINE PHOSPHATASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALKALINE PHOSPHATASE, MALEIC ACID, ...
Authors:De Backer, M.E, Mc Sweeney, S, Rasmussen, H.B, Riise, B.W, Lindley, P, Hough, E.
Deposit date:2001-10-19
Release date:2002-07-31
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase
J.Mol.Biol., 318, 2002
7BB5
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BU of 7bb5 by Molmil
Crystal structure of anti-CRISPR protein AcrIF9
Descriptor: AcrIF9
Authors:Tamulaitiene, G, Sinkunas, T, Kupcinskaite, E.
Deposit date:2020-12-17
Release date:2021-11-24
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Disarming of type I-F CRISPR-Cas surveillance complex by anti-CRISPR proteins AcrIF6 and AcrIF9.
Sci Rep, 12, 2022
9FK0
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BU of 9fk0 by Molmil
LGTV with TBEV prME
Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, ...
Authors:Bisikalo, K, Rosendal, E.
Deposit date:2024-06-01
Release date:2024-11-06
Last modified:2024-11-27
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:The influence of the pre-membrane and envelope proteins on structure, pathogenicity and tropism of tick-borne encephalitis virus
Biorxiv, 2024

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數據於2025-07-23公開中

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