PDB: 17012 resultsInfo pagesStatus searchChemie searchBIRD

---

3KVX	JNK3 bound to aminopyrimidine inhibitor, SR-3562 Descriptor: Mitogen-activated protein kinase 10, N-[(2Z)-4-(3-fluoro-5-morpholin-4-ylphenyl)pyrimidin-2(1H)-ylidene]-4-(3-morpholin-4-yl-1H-1,2,4-triazol-1-yl)aniline Authors: Habel, J.E, Laughlin, J.D, LoGrasso, P. Deposit date: 2009-11-30 Release date: 2009-12-22 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Synthesis, Biological Evaluation, X-ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) Inhibitors J.Med.Chem., 53, 2010
1NBE	ASPARTATE TRANSCARBAMOYLASE REGULATORY CHAIN MUTANT (T82A) Descriptor: ASPARTATE TRANSCARBAMOYLASE, D-MALATE, ZINC ION Authors: Williams, M.K, Stec, B, Kantrowitz, E.R. Deposit date: 1998-04-25 Release date: 1998-10-14 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A single mutation in the regulatory chain of Escherichia coli aspartate transcarbamoylase results in an extreme T-state structure. J.Mol.Biol., 281, 1998
4WYO	Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 1 Descriptor: 2'-tert-butyl-1-(2H-indazol-5-ylcarbonyl)-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazol]-7'(6'H)-one, Acetyl-CoA carboxylase Authors: Vajdos, F.F. Deposit date: 2014-11-17 Release date: 2015-01-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. J.Med.Chem., 57, 2014
1O07	Crystal Structure of the complex between Q120L/Y150E mutant of AmpC and a beta-lactam inhibitor (MXG) Descriptor: 2-(1-{2-[4-(2-ACETYLAMINO-PROPIONYLAMINO)-4-CARBOXY-BUTYRYLAMINO]-6-AMINO-HEXANOYLAMINO}-2-OXO-ETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase, POTASSIUM ION Authors: Meroueh, S.O, Minasov, G, Lee, W, Shoichet, B.K, Mobashery, S. Deposit date: 2003-02-20 Release date: 2003-08-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Structural Aspects for Evolution of beta-Lactamases from Penicillin-Binding Proteins J.Am.Chem.Soc., 125, 2003
4XW0	Crystal structure of (GCCU(G-LNA)CCUGC)2 duplex Descriptor: RNA (5'-R(*GP*CP*CP*UP*(LCG)P*CP*CP*UP*GP*C)-3'), SULFATE ION Authors: Kiliszek, A, Banaszak, K, Rypniewski, W. Deposit date: 2015-01-28 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation. Rna, 22, 2016
1P6Y	T4 LYSOZYME CORE REPACKING MUTANT M120Y/TA Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... Authors: Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. Deposit date: 2003-04-30 Release date: 2003-10-07 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003
4XW1	Crystal structure of (GCCU(G-LNA)CCUG)2 duplex Descriptor: RNA (5'-R(*GP*CP*CP*UP*(LCG)P*CP*CP*UP*G)-3') Authors: Kiliszek, A, Banaszak, K, Rypniewski, W. Deposit date: 2015-01-28 Release date: 2016-01-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.302 Å) Cite: Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation. Rna, 22, 2016
1OKB	crystal structure of Uracil-DNA glycosylase from Atlantic cod (Gadus morhua) Descriptor: CHLORIDE ION, GLYCEROL, URACIL-DNA GLYCOSYLASE Authors: Leiros, I, Moe, E, Lanes, O, Smalas, A.O, Willassen, N.P. Deposit date: 2003-07-21 Release date: 2004-04-05 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Crystal Structure of Uracil-DNA Glycosylase from Atlantic Cod (Gadus Morhua) Reveals Cold-Adaptation Features Acta Crystallogr.,Sect.D, 59, 2003
1P64	T4 LYSOZYME CORE REPACKING MUTANT L133F/TA Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... Authors: Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. Deposit date: 2003-04-28 Release date: 2003-10-07 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Repacking the Core of T4 lysozyme by automated design J.Mol.Biol., 332, 2003
5M5C	Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins Descriptor: Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-P, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J. Deposit date: 2016-10-21 Release date: 2017-10-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nat. Struct. Mol. Biol., 24, 2017
1P2L	T4 Lysozyme Core Repacking Mutant V87I/TA Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... Authors: Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. Deposit date: 2003-04-15 Release date: 2003-10-07 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Repacking the Core of T4 lysozyme by automated design J.Mol.Biol., 332, 2003
5M50	Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins Descriptor: Calmodulin-regulated spectrin-associated protein 3, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-P, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J. Deposit date: 2016-10-20 Release date: 2017-10-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (5.3 Å) Cite: A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nat. Struct. Mol. Biol., 24, 2017
1P2R	T4 LYSOZYME CORE REPACKING MUTANT I78V/TA Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... Authors: Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. Deposit date: 2003-04-15 Release date: 2003-10-07 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Repacking the Core of T4 lysozyme by automated design J.Mol.Biol., 332, 2003
1P3H	Crystal Structure of the Mycobacterium tuberculosis chaperonin 10 tetradecamer Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 10 kDa chaperonin, CALCIUM ION Authors: Roberts, M.M, Coker, A.R, Fossati, G, Mascagni, P, Coates, A.R.M, Wood, S.P, TB Structural Genomics Consortium (TBSGC) Deposit date: 2003-04-17 Release date: 2003-07-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops J.BACTERIOL., 185, 2003
4XXW	Crystal structure of mouse Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 splice variant Descriptor: CALCIUM ION, CHLORIDE ION, Cadherin-23, ... Authors: Narui, Y, Sotomayor, M. Deposit date: 2015-01-31 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.261 Å) Cite: Tuning Inner-Ear Tip-Link Affinity Through Alternatively Spliced Variants of Protocadherin-15. Biochemistry, 57, 2018
1P36	T4 LYOSZYME CORE REPACKING MUTANT I100V/TA Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME, ... Authors: Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. Deposit date: 2003-04-16 Release date: 2003-10-07 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Repacking the Core of T4 lysozyme by automated design J.Mol.Biol., 332, 2003
1OYH	Crystal Structure of P13 Alanine Variant of Antithrombin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, ... Authors: Johnson, D.J.D, Huntington, J.A. Deposit date: 2003-04-04 Release date: 2004-04-13 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.62 Å) Cite: The influence of hinge region residue Glu-381 on antithrombin allostery and metastability J.Biol.Chem., 279, 2004
316D	Selectivity of F8-actinomycin D for RNA:DNA hybrids and its anti-leukemia activity Descriptor: 8-FLUORO-ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') Authors: Takusagawa, F, Takusagawa, K.T, Carlson, R.G, Weaver, R.F. Deposit date: 1997-03-05 Release date: 1997-11-05 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (3 Å) Cite: Selectivity of F8-Actinomycin D for RNA:DNA Hybrids and its Anti-Leukemia Activity. Bioorg.Med.Chem., 5, 1997
1PDC	REFINED SOLUTION STRUCTURE AND LIGAND-BINDING PROPERTIES OF PDC-109 DOMAIN B. A COLLAGEN-BINDING TYPE II DOMAIN Descriptor: SEMINAL FLUID PROTEIN PDC-109 Authors: Llinas, M, Constantine, K.L, Patthy, L. Deposit date: 1991-10-10 Release date: 1994-01-31 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Refined solution structure and ligand-binding properties of PDC-109 domain b. A collagen-binding type II domain. J.Mol.Biol., 223, 1992
1PEW	High Resolution Crystal Structure of Jto2, a mutant of the non-amyloidogenic Lamba6 Light Chain, Jto Descriptor: CADMIUM ION, Jto2, a LAMBDA-6 TYPE IMMUNOGLOBULIN LIGHT CHAIN, ... Authors: Dealwis, C, Gupta, V, Wilkerson, M. Deposit date: 2003-05-22 Release date: 2004-07-13 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four V(lambda)6 proteins J.Mol.Recog., 17, 2004
1PG5	CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS Descriptor: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION Authors: De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J. Deposit date: 2003-05-27 Release date: 2004-06-08 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius. J.Mol.Biol., 339, 2004
1PYZ	CRYSTALLOGRAPHIC STRUCTURE OF MIMOCHROME IV Descriptor: CHLORIDE ION, CO(III)-(DEUTEROPORPHYRIN IX), MIMOCHROME IV, ... Authors: Di Costanzo, L, Geremia, S, Randaccio, L, Nastri, F, Maglio, O, Lombardi, A, Pavone, V. Deposit date: 2003-07-09 Release date: 2004-12-14 Last modified: 2018-06-27 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Miniaturized heme proteins: crystal structure of Co(III)-mimochrome IV. J.Biol.Inorg.Chem., 9, 2004
4YPD	Crystal Structure of DAPK1 catalytic domain in complex with the hinge binding fragment 4-methylpyridazine Descriptor: 4-methylpyridazine, CHLORIDE ION, Death-associated protein kinase 1, ... Authors: Grum-Tokars, V.L, Minasov, G, Roy, S.M, Anderson, W.F, Watterson, D.M. Deposit date: 2015-03-12 Release date: 2015-05-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal Structure of DAPK1 catalytic domain in complex with hinge binding fragments To Be Published
1PQI	T4 LYSOZYME CORE REPACKING MUTANT I118L/CORE7/TA Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme, ... Authors: Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. Deposit date: 2003-06-18 Release date: 2003-10-07 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003
4Y52	Crystal structure of 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation. Descriptor: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... Authors: Wang, L, Chong, J, Wang, D. Deposit date: 2015-02-11 Release date: 2015-07-15 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. Nature, 523, 2015

<87888990919293949596979899100101102>