1O07

Crystal Structure of the complex between Q120L/Y150E mutant of AmpC and a beta-lactam inhibitor (MXG)

Summary for 1O07

Entry DOI	10.2210/pdb1o07/pdb
Descriptor	Beta-lactamase, POTASSIUM ION, 2-(1-{2-[4-(2-ACETYLAMINO-PROPIONYLAMINO)-4-CARBOXY-BUTYRYLAMINO]-6-AMINO-HEXANOYLAMINO}-2-OXO-ETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, ... (4 entities in total)
Functional Keywords	enzyme inhibitor complex, beta-lactamase beta-lactam complex, hydrolase
Biological source	Escherichia coli
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	80325.26
Authors	Meroueh, S.O.,Minasov, G.,Lee, W.,Shoichet, B.K.,Mobashery, S. (deposition date: 2003-02-20, release date: 2003-08-26, Last modification date: 2024-04-03)
Primary citation	Meroueh, S.O.,Minasov, G.,Lee, W.,Shoichet, B.K.,Mobashery, S. Structural Aspects for Evolution of beta-Lactamases from Penicillin-Binding Proteins J.Am.Chem.Soc., 125:9612-9618, 2003 Cited by PubMed: 12904027 DOI: 10.1021/ja034861u PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.71 Å)

Structure validation