8VEN
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![BU of 8ven by Molmil](/molmil-images/mine/8ven) | Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 in complex with cefoperazone | Descriptor: | (2R,4R)-2-[(1R)-1-{[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5-methylidene-1,3-thiazinane-4-carboxylic acid, Probable peptidoglycan D,D-transpeptidase PenA | Authors: | Stratton, C, Bala, S, Davies, C. | Deposit date: | 2023-12-20 | Release date: | 2024-03-20 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041. Acs Infect Dis., 10, 2024
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9BKL
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8WCN
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![BU of 8wcn by Molmil](/molmil-images/mine/8wcn) | Cryo-EM structure of PAO1-ImcA with GMPCPP | Descriptor: | Diguanylate cyclase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Zhan, X.L, Zhang, K, Wang, C.C, Fan, Q, Tang, X.J, Zhang, X, Wang, K, Fu, Y, Liang, H.H. | Deposit date: | 2023-09-13 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa. Nat Commun, 15, 2024
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8Z10
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![BU of 8z10 by Molmil](/molmil-images/mine/8z10) | Human beta-catenin crystal structure | Descriptor: | Catenin beta-1, PROLINE | Authors: | Tim, F. | Deposit date: | 2024-04-10 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of Beta-catenin To Be Published
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8ZWH
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8Z5J
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![BU of 8z5j by Molmil](/molmil-images/mine/8z5j) | Beta-catenin Crystal Structure | Descriptor: | Catenin beta-1 | Authors: | Tim, F. | Deposit date: | 2024-04-18 | Release date: | 2024-05-22 | Last modified: | 2024-08-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells. J.Med.Chem., 67, 2024
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9FX5
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![BU of 9fx5 by Molmil](/molmil-images/mine/9fx5) | Crystal structure of Cryo2RT Thaumatin at 296K | Descriptor: | L(+)-TARTARIC ACID, Thaumatin I | Authors: | Huang, C.Y, Aumonier, S, Olieric, V, Wang, M. | Deposit date: | 2024-07-01 | Release date: | 2024-07-31 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.592 Å) | Cite: | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals. Acta Crystallogr D Struct Biol, 80, 2024
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8W9P
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![BU of 8w9p by Molmil](/molmil-images/mine/8w9p) | Structure of full Banna virus | Descriptor: | VP10, VP2, VP4, ... | Authors: | Li, Z, Cao, S. | Deposit date: | 2023-09-05 | Release date: | 2024-03-27 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Cryo-EM structures of Banna virus in multiple states reveal stepwise detachment of viral spikes. Nat Commun, 15, 2024
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8X70
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![BU of 8x70 by Molmil](/molmil-images/mine/8x70) | The Crystal Structure of IFI16 from Biortus. | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, Gamma-interferon-inducible protein 16, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Meng, Q, Wang, J. | Deposit date: | 2023-11-22 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of IFI16 from Biortus. To Be Published
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9FT0
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![BU of 9ft0 by Molmil](/molmil-images/mine/9ft0) | Yeast 20S proteasome in complex with epoxyketone inhibitor 42 | Descriptor: | (2S)-N-[(2S)-1-[[(1S)-2-cyclohexyl-1-[(2R,3S,6R,7S)-3-methanoyl-2,6-dimethyl-6,7-bis(oxidanyl)-1,4-oxazepan-7-yl]ethyl]amino]-3-(4-methoxyphenyl)-1-oxidanylidene-propan-2-yl]-2-(2-morpholin-4-ylethanoylamino)-4-oxidanyl-butanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | Deposit date: | 2024-06-23 | Release date: | 2024-07-10 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites to be published
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8Y2U
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![BU of 8y2u by Molmil](/molmil-images/mine/8y2u) | Crystal structure of 3C protease from coxsackievirus B4 | Descriptor: | Protease 3C | Authors: | Jiang, H.H, Lin, C, Zhang, J, Li, J. | Deposit date: | 2024-01-27 | Release date: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structures of the 3C proteases from Coxsackievirus B3 and B4. Acta Crystallogr.,Sect.F, 80, 2024
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8Y14
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![BU of 8y14 by Molmil](/molmil-images/mine/8y14) | Beta-catenin Crystal Structure | Descriptor: | Catenin beta-1 | Authors: | Tim, F. | Deposit date: | 2024-01-23 | Release date: | 2024-03-13 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Beta-catenin Crystal Structure To Be Published
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9B56
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8XFZ
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![BU of 8xfz by Molmil](/molmil-images/mine/8xfz) | The structure of HLA-A/L1-2 | Descriptor: | Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1 | Authors: | Zhang, J.N, Yue, C, Liu, J. | Deposit date: | 2023-12-14 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals. Immunohorizons, 8, 2024
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8WWU
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![BU of 8wwu by Molmil](/molmil-images/mine/8wwu) | 1-naphthylamine GS in complex with AMP PNP | Descriptor: | Glutamine synthetase, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Zhang, S.T, Zhou, N.Y. | Deposit date: | 2023-10-26 | Release date: | 2024-01-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of the 1-naphthylamine biodegradation pathway reveals a glutamine synthetase-like protein that catalyzes 1-naphthylamine glutamylation To Be Published
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8VJC
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![BU of 8vjc by Molmil](/molmil-images/mine/8vjc) | Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | Descriptor: | Insulin-like growth factor II, Isoform Short of Insulin receptor | Authors: | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | Deposit date: | 2024-01-06 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
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8YF8
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9BHW
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8VAP
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9B5B
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8W9R
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![BU of 8w9r by Molmil](/molmil-images/mine/8w9r) | Structure of Banna virus core | Descriptor: | VP10, VP8, Vp2 | Authors: | Li, Z, Cao, S. | Deposit date: | 2023-09-05 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Cryo-EM structures of Banna virus in multiple states reveal stepwise detachment of viral spikes. Nat Commun, 15, 2024
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6R6A
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![BU of 6r6a by Molmil](/molmil-images/mine/6r6a) | Major aspartyl peptidase 1 from C. neoformans | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Endopeptidase, ... | Authors: | Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. | Deposit date: | 2019-03-26 | Release date: | 2021-04-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery. J.Med.Chem., 64, 2021
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8XAT
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9END
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![BU of 9end by Molmil](/molmil-images/mine/9end) | Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 3 | Descriptor: | CHLORIDE ION, Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Coquille, S, Roche, J, Girard, E, Madern, D. | Deposit date: | 2024-03-12 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Navigating the conformational landscape of an enzyme. Stabilization of a low populated conformer by evolutionary mutations triggers Allostery into a non-allosteric enzyme. To be published
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8XKC
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![BU of 8xkc by Molmil](/molmil-images/mine/8xkc) | The structure of HLA-A/Pep16 | Descriptor: | Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1 | Authors: | Zhang, J.N, Yue, C, Liu, J. | Deposit date: | 2023-12-23 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals. Immunohorizons, 8, 2024
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